Explore
Validate
Learn
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- HPA004727 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA004727, RRID:AB_1079074
- Product name
- Anti-HMGCL
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human HMGCL, Gene description: 3-hydroxymethyl-3-methylglutaryl-CoA lyase, Alternative Gene Names: HL, Validated applications: IHC, WB, Uniprot ID: P35914, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Prostate cancer castrate resistant progression usage of non-canonical androgen receptor signaling and ketone body fuel
Dysregulation of Ketone Body Metabolism Is Associated With Poor Prognosis for Clear Cell Renal Cell Carcinoma Patients
Inactivation of HMGCL promotes proliferation and metastasis of nasopharyngeal carcinoma by suppressing oxidative stress
Ketone bodies and two-compartment tumor metabolism: Stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells
Labanca E, Bizzotto J, Sanchis P, Anselmino N, Yang J, Shepherd P, Paez A, Antico-Arciuch V, Lage-Vickers S, Hoang A, Tang X, Raso M, Titus M, Efstathiou E, Cotignola J, Araujo J, Logothetis C, Vazquez E, Navone N, Gueron G
Oncogene 2021;40(44):6284-6298
Oncogene 2021;40(44):6284-6298
Dysregulation of Ketone Body Metabolism Is Associated With Poor Prognosis for Clear Cell Renal Cell Carcinoma Patients
Cui W, Luo W, Zhou X, Lu Y, Xu W, Zhong S, Feng G, Liang Y, Liang L, Mo Y, Xiao X, Huang G, Matskova L, Zhang Z, Li P, Zhou X
Frontiers in Oncology 2019;9
Frontiers in Oncology 2019;9
Inactivation of HMGCL promotes proliferation and metastasis of nasopharyngeal carcinoma by suppressing oxidative stress
Luo W, Qin L, Li B, Liao Z, Liang J, Xiao X, Xiao X, Mo Y, Huang G, Zhang Z, Zhou X, Li P
Scientific Reports 2017;7(1)
Scientific Reports 2017;7(1)
Ketone bodies and two-compartment tumor metabolism: Stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells
Martinez-Outschoorn U, Lin Z, Whitaker-Menezes D, Howell A, Lisanti M, Sotgia F
Cell Cycle 2014;11(21):3956-3963
Cell Cycle 2014;11(21):3956-3963
No comments: Submit comment
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human liver and skin tissues using Anti-HMGCL antibody. Corresponding HMGCL RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
