27935-1-AP

antibody from Proteintech Group

Targeting: WNT1 INT1

Provider product page for 27935-1-AP

Western blot

ELISA

Antibody data

Antibody Data
Antigen structure
References [60]
Comments [0]
Validations [0]

Submit

Product number: 27935-1-AP - Provider product page
Provider: Proteintech Group
Product name: WNT1 antibody
Antibody type: Polyclonal
Description: KD/KO validated WNT1 antibody (Cat. #27935-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, mouse and has been validated for the following applications: WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

WNT1 protein structure - 27935-1-AP shown in red.

Submitted references Piezo1-mediated mechanotransduction regulates diabetic osteoporosis and hyperglycemia via low-intensity pulsed ultrasound.

Cao M, Pang F, Duan X, Sun L, Fan X, Tang L, Ta D
Bone 2026 Jan;202:117664

Liu Wei Di Huang Decoction Alleviates Renal Fibrosis by Inhibiting Endothelial Mesenchymal Transitions via Upregulating Sirt1 Expression and Inhibiting the Wnt/β-Catenin Signaling Pathway.

Wang H, Chen SS, Zhang YX, Gao HB, Meng B, Wu WY, Tang Q
Drug design, development and therapy 2025;19:6587-6603

ZNF710 regulates the proliferation, migration, apoptosis, and cell cycle progression of gastric cancer cells through the Wnt/β-catenin pathway.

Zhou R, Zhou J, Cai J, Wen J, Wang F, Ma D, Luo Q, Yalikun A, Han J, Zhou X, Yu Y, Li Q, Wen Y
American journal of cancer research 2025;15(12):5266-5280

The role of the Wnt/BDNF pathway in maternal SCH-induced autism-like phenotypes in offspring rats: behavioral and molecular mechanisms.

Liu D, Tao K, Sun Y, Hao J, Wang S
Translational psychiatry 2025 Oct 7;15(1):387

FoxO3 controls cardiomyocyte proliferation and heart regeneration by regulating Sfrp2 expression in postnatal mice.

Xia JB, Liu K, Lin XL, Li HJ, Lin JH, Li L, Liang CQ, Cao Y, Wen N, Liao ZF, Zhao H, Park KS, Song GH, Ye ZB, Cai DQ, Ju ZY, Qi XF
Nature communications 2025 Mar 14;16(1):2532

TOP2A Promotes Proliferation, Migration, and Inflammatory Response in M5-Treated Keratinocytes by Binding CTBP1 to Activate Wnt/β-Catenin Signaling.

Yang Y, Liu S, Xiao X
Cell biochemistry and biophysics 2025 Jun;83(2):2101-2113

MMP3 as a new target of Danshensu/tetramethylpyrazine derivative for attenuating cardiac fibrosis post-myocardial infarction.

Huang W, He C, In Kim H, Gao X, You J, Shao T, Liu Y, Wei H, Wang Y, Wang J, Xu Y, Guo J
Life sciences 2025 Jun 1;370:123570

Polyporus Umbellatus polysaccharide ameliorates rheumatoid arthritis via inhibiting inflammation and regulating gut microbiota.

Zheng Z, Dai J, Pan X, Xiang J, You P, Zhang H, Luo L
International journal of biological macromolecules 2025 Jul;318(Pt 4):145306

HMGB1 Accelerates Wound Healing by Promoting the Differentiation of Epidermal Stem Cells via the "HMGB1-TLR4-Wnt/Notch" Axis.

Zhen M, Zhu Y, Wang P, Liu X, Zhu J, Liu H, Li J, Zhao J, Shu B
Advances in wound care 2025 Jul;14(7):365-380

Microglial exosome TREM2 ameliorates ferroptosis and neuroinflammation in alzheimer's disease by activating the Wnt/β-catenin signaling.

Zhu L, Zhou T, Wu L, Zhu X, Chen L, Zhang M, Zhou J, Wang F
Scientific reports 2025 Jul 10;15(1):24968

Mechanism of Buyang Huanwu Decoction mediating Cav1-regulated Wnt pathway to promote neural regeneration in cerebral ischemic mice.

OuYang Y, Yi J, Chen B, Zeng F, Chen X, Yang H, Xu Y, Liu Z, Ning W, Liu B
Journal of ethnopharmacology 2025 Jan 13;339:119121

miR-124-3p inhibits CRC proliferation, migration, and invasion by targeting ITGB1.

Li J, Liu L
Discover oncology 2025 Feb 11;16(1):158

Weight-Bearing Ladder Climbing Exercise Improves Bone Loss and Bone Microstructural Damage While Promoting Bone Injury Healing in OVX Rats.

Kang Y, Li N, Yu Y, Wang D, Zhao T, Sun L, Liu C, Tang L
Biology 2025 Dec 28;15(1)

Direct and indirect effects of transforming growth factor-beta on osteoclast-mediated bone remodeling using a new in vitro bone matrix model.

Chiba-Ohkuma R, Karakida T, Yamamoto R, Yamakoshi Y
JBMR plus 2025 Aug;9(8):ziaf104

GPR30 Inhibits Neuronal Apoptosis After Subarachnoid Hemorrhage by Activating the Wnt/β-Catenin Pathway in a m6A-dependent Manner.

Peng J, He J, Hu X, Xia Y
Molecular neurobiology 2025 Aug;62(8):9638-9650

A novel peptide RR-171 derived from human umbilical cord serum induces apoptosis and pyroptosis in pancreatic cancer cells.

Chen W, Yang K, Liu X, Cheng X, Zhu D, Yang Z, Chen Y
Scientific reports 2025 Apr 14;15(1):12819

Protocol for evaluating the effects of large gradient high magnetic fields on osteocyte function.

Zhang B, Shang P
STAR protocols 2024 Sep 20;5(3):103186

Wnt/β-catenin signaling inhibits oxidative stress-induced ferroptosis to improve interstitial cystitis/bladder pain syndrome by reducing NF-κB.

Fang W, Song X, Li H, Meng F, Lv T, Huang J, Ji X, Lv J, Cai Z, Wang Z
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119766

A novel antidepressant homogeneous polysaccharide YLP-1 from Millettia pulchra ameliorates tryptophan metabolism and SCFAs through modulating gut microbiota.

Yu M, Cai CC, Huang YF, Zhu YD, Luo XY, Kong XY, Zhang WT, Li HJ, Fang JX, Zou ZM
Carbohydrate polymers 2024 Nov 15;344:122527

Mechanical strain regulates osteogenesis via Antxr1/LncRNA H19/Wnt/β-catenin axis.

Liu L, Guo J, Tong X, Zhang M, Chen X, Huang M, Zhu C, Bennett S, Xu J, Zou J
Journal of cellular physiology 2024 May;239(5):e31214

NAT1 inhibits liver metastasis of colorectal cancer by regulating EMT and glycolysis.

Gu W, Li C, Shen T, Tong L, Yuan W, Zheng X, Wang T, Wang S, Zhu B, Zhang C, Zhang C
Aging 2024 Jun 24;16(12):10546-10562

Mangiferin alleviates 6-OHDA-induced Parkinson's disease by inhibiting AKR1C3 to activate Wnt signaling pathway.

Huang W, Wang Y, Huang W
Neuroscience letters 2024 Jan 31;821:137608

Microplastics cause hepatotoxicity in diabetic mice by disrupting glucolipid metabolism via PP2A/AMPK/HNF4A and promoting fibrosis via the Wnt/β-catenin pathway.

Li X, Feng L, Kuang Q, Wang X, Yang J, Niu X, Gao L, Huang L, Luo P, Li L
Environmental toxicology 2024 Feb;39(2):1018-1030

Loureirin A Promotes Cell Differentiation and Suppresses Migration and Invasion of Melanoma Cells via WNT and AKT/mTOR Signaling Pathways.

Xia ZY, Liu L, Kuok CF, Wang XL, Shi D, Ma Q, Cheng XY, Wang GL, Li MJ, Zheng QS, Liu XN, Li DF, Li BH
Biological & pharmaceutical bulletin 2024 Feb 22;47(2):486-498

LncRNA MALAT1 to Enhance Pyroptosis in Viral Myocarditis Through UPF1-Mediated SIRT6 mRNA Decay and Wnt-β-Catenin Signal Pathway.

Zeng M, Chen Z, Wang Y, Yang Z, Xiang J, Wang X, Wang X
Cardiovascular toxicology 2024 Dec;24(12):1439-1454

A 0.2 T-0.4 T Static Magnetic Field Improves the Bone Quality of Mice Subjected to Hindlimb Unloading and Reloading Through the Dual Regulation of BMSCs via Iron Metabolism.

Wang J, Zhen C, Zhang G, Yang Z, Shang P
International journal of molecular sciences 2024 Dec 6;25(23)

Long non-coding RNA NEAT1 induced by BHLHE40 activates Wnt/β-catenin signaling and potentiates colorectal cancer progression.

Ji A, Li H, Fu X, Zhang Y, Liu Y
Cell division 2024 Aug 4;19(1):25

Homologous Tumor Cell-Derived Biomimetic Nano-Trojan Horse Integrating Chemotherapy with Genetherapy for Boosting Triple-Negative Breast Cancer Therapy.

Duan W, Shen Q, Ju L, Huang Z, Geng J, Wu Q, Yu C, Wei J
ACS applied materials & interfaces 2024 Aug 28;16(34):45523-45536

QiHuangYiShen Granules Modulate the Expression of LncRNA MALAT1 and Attenuate Epithelial-Mesenchymal Transition in Kidney of Diabetic Nephropathy Rats.

Yuan LS, Du H, Ren QY, Yang RL, Liu SW, Liu SY, Shi KF, Wang B, Meng XF, Li TX, Zhang N
Evidence-based complementary and alternative medicine : eCAM 2023;2023:3357281

LncRNA RPPH1 acts as a molecular sponge for miR-122 to regulate Wnt1/β-catenin signaling in hepatocellular carcinoma.

Zhou J, Shi K, Huang W, Zhang Y, Chen Q, Mou T, Wu Z, Wei X
International journal of medical sciences 2023;20(1):23-34

Genetic modification of miR-34a enhances efficacy of transplanted human dental pulp stem cells after ischemic stroke.

Wang J, He P, Tian Q, Luo Y, He Y, Liu C, Gong P, Guo Y, Ye Q, Li M
Neural regeneration research 2023 Sep;18(9):2029-2036

Voluntary wheel-running improved pulmonary fibrosis by reducing epithelial mesenchymal transformation.

Gao Y, Yang Z, He K, Wang Z, Zhang T, Yi J, Zhao L
Life sciences 2023 Oct 15;331:122066

BMSCs alleviate liver cirrhosis by regulating Fstl1/Wnt/β-Catenin signaling pathway.

Zhangdi H, Geng X, Li N, Xu R, Hu Y, Liu J, Zhang X, Qi J, Tian Y, Qiu J, Huang S, Cang X, Jin S
Heliyon 2023 Nov;9(11):e21010

Prolonged exposure to the herbicide atrazine promotes kidney fibrosis by activating Wnt/β-catenin signaling in rats.

Wang T, Huang X, Liu J, Liu W, Yang Z, He K, Chen J, Zhao L
Environmental toxicology 2023 May;38(5):1143-1152

Genotypic and Phenotypic Spectrum and Pathogenesis of WNT1 Variants in a Large Cohort of Patients With OI/Osteoporosis.

Hu J, Lin X, Gao P, Zhang Q, Zhou B, Wang O, Jiang Y, Xia W, Xing X, Li M
The Journal of clinical endocrinology and metabolism 2023 Jun 16;108(7):1776-1786

The protective effect of lncRNA NEAT1/miR-122-5p/Wnt1 axis on hippocampal damage in hepatic ischemic reperfusion young mice.

Dong Z, Jia L, Han W, Wang Y, Sheng M, Ren Y, Weng Y, Li H, Yu W
Cellular signalling 2023 Jul;107:110668

Hepatoprotective effect of protocatechuic acid against type 2 diabetes-induced liver injury.

Xu K, Lu G, Feng Q, Chen S, Wang Y
Pharmaceutical biology 2023 Dec;61(1):737-745

IGF2BP1 facilitates non-small cell lung cancer progression by regulating the KIF2A-mediated Wnt/β-catenin pathway.

Sun M, Wang L, Ge L, Xu D, Zhang R
Functional & integrative genomics 2023 Dec 15;24(1):4

Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway.

Zhang B, Li X, Zhou X, Lou C, Wang S, Lv H, Zhang G, Fang Y, Yin D, Shang P
iScience 2023 Aug 18;26(8):107365

Thymopentin-Mediated Inhibition of Cancer Stem Cell Stemness Enhances the Cytotoxic Effect of Oxaliplatin on Colon Cancer Cells.

Yu PC, Liu D, Han ZX, Liang F, Hao CY, Lei YT, Guo CR, Wang WH, Li XH, Yang XN, Li CZ, Yu Y, Fan YZ
Frontiers in pharmacology 2022;13:779715

Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.

Wang H, Zhao S, Liu Y, Sun F, Huang X, Wu T
Frontiers in oncology 2022;12:898047

SEL1L-HRD1 ER-associated degradation suppresses hepatocyte hyperproliferation and liver cancer.

Bhattacharya A, Wei J, Song W, Gao B, Tian C, Wu SA, Wang J, Chen L, Fang D, Qi L
iScience 2022 Oct 21;25(10):105183

Non-canonical Wnt/calcium signaling is protective against podocyte injury and glomerulosclerosis.

Zhou D, Wang Y, Gui Y, Fu H, Zhou S, Wang Y, Bastacky SI, Stolz DB, Liu Y
Kidney international 2022 Jul;102(1):96-107

Luteolin alleviates ischemia/reperfusion injury-induced no-reflow by regulating Wnt/β-catenin signaling in rats.

Qin X, Qin H, Li Z, Xue S, Huang B, Liu X, Wang D
Microvascular research 2022 Jan;139:104266

Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.

Tang W, Xue J, Luo L, Wang Y, Cai X, Liu Y, Huang D, Wang X, He T, Lu D, Yang F
Molecular medicine reports 2022 Feb;25(2)

FAT4 activation inhibits epithelial-mesenchymal transition (EMT) by promoting autophagy in H2228/Cer cells.

Yang Y, Li Y, Yang Q, Liu Z, Chang X, Yang H, Liu J, Li Z, Zuo D
Medical oncology (Northwood, London, England) 2022 Dec 28;40(1):64

SEC14L3 plays a tumor-suppressive role in breast cancer through a Wnt/β-catenin-related way.

Zhu Q, Wan NB, Deng HW, Lu LL, Zhang Y, He X, Liu H, He Y
Experimental cell research 2022 Aug 1;417(1):113161

A noncoding regulatory RNA Gm31932 induces cell cycle arrest and differentiation in melanoma via the miR-344d-3-5p/Prc1 (and Nuf2) axis.

Wang D, Chen J, Li B, Jiang Q, Liu L, Xia Z, Zheng Q, Li M, Li D
Cell death & disease 2022 Apr 7;13(4):314

Expression of TCF3 in Wilms' tumor and its regulatory role in kidney tumor cell viability, migration and apoptosis in vitro.

Zhou N, Yan B, Ma J, Jiang H, Li L, Tang H, Ji F, Yao Z
Molecular medicine reports 2021 Sep;24(3)

Combination of an engineered Lactococcus lactis expressing CXCL12 with light-emitting diode yellow light as a treatment for scalded skin in mice.

Zhao X, Li S, Ding J, Wei J, Tian P, Wei H, Chen T
Microbial biotechnology 2021 Sep;14(5):2090-2100

ODAM promotes junctional epithelium-related gene expression via activation of WNT1 signaling pathway in an ameloblast-like cell line ALC.

Song D, Yang S, Tan T, Wang R, Ma Z, Wang Y, Wang L
Journal of periodontal research 2021 Jun;56(3):482-491

MiR-130a-3p suppresses colorectal cancer growth by targeting Wnt Family Member 1 (WNT1).

Song GL, Xiao M, Wan XY, Deng J, Ling JD, Tian YG, Li M, Yin J, Zheng RY, Tang Y, Liu GY
Bioengineered 2021 Dec;12(1):8407-8418

Hyperin Controls the Development and Therapy of Gastric Cancer via Regulating Wnt/β-Catenin Signaling.

Ping MH
Cancer management and research 2020;12:11773-11782

Agmatine Attenuates Liver Ischemia Reperfusion Injury by Activating Wnt/β-catenin Signaling in Mice.

Han Z, Li Y, Yang B, Tan R, Wang M, Zhang B, Dai C, Wei L, Chen D, Chen Z
Transplantation 2020 Sep;104(9):1906-1916

miR‑483‑3p promotes the osteogenesis of human osteoblasts by targeting Dikkopf 2 (DKK2) and the Wnt signaling pathway.

Zhou B, Peng K, Wang G, Chen W, Liu P, Chen F, Kang Y
International journal of molecular medicine 2020 Oct;46(4):1571-1581

MSCs reduce airway remodeling in the lungs of asthmatic rats through the Wnt/β-catenin signaling pathway.

Song J, Zhu XM, Wei QY
European review for medical and pharmacological sciences 2020 Nov;24(21):11199-11211

Exercise Promotes the Osteoinduction of HA/β-TCP Biomaterials via the Wnt Signaling Pathway.

Cheng L, Khalaf AT, Lin T, Ran L, Shi Z, Wan J, Zhou X, Zou L
Metabolites 2020 Mar 5;10(3)

Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway.

Sha L, Ma D, Chen C
Aging 2020 Dec 13;12(23):23598-23608

Wu-Mei-Wan ameliorates chronic colitis-associated intestinal fibrosis through inhibiting fibroblast activation.

Wu F, Shao Q, Hu M, Zhao Y, Dong R, Fang K, Xu L, Zou X, Lu F, Li J, Chen G
Journal of ethnopharmacology 2020 Apr 24;252:112580

RFC3 induces epithelial‑mesenchymal transition in lung adenocarcinoma cells through the Wnt/β‑catenin pathway and possesses prognostic value in lung adenocarcinoma.

Gong S, Qu X, Yang S, Zhou S, Li P, Zhang Q
International journal of molecular medicine 2019 Dec;44(6):2276-2288

No comments: Submit comment

No validations: Submit validation data