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- Antigen structure
- References [14]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 15116-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15116-1-AP, RRID:AB_2119959
- Product name
- HSD17B4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HSD17B4 antibody (Cat. #15116-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism.
Germ cell-specific deletion of Pex3 reveals essential roles of PEX3-dependent peroxisomes in spermiogenesis.
Cell Type-Selective Loss of Peroxisomal β-Oxidation Impairs Bipolar Cell but Not Photoreceptor Survival in the Retina.
In Situ Peroxidase Labeling Followed by Mass-Spectrometry Reveals TIA1 Interactome.
Quantitative proteomic analysis identified differentially expressed proteins with tail/rump fat deposition in Chinese thin- and fat-tailed lambs.
Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice.
The Peroxisomal Localization of Hsd17b4 Is Regulated by Its Interaction with Phosphatidylserine.
WHSC1 Promotes Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma by Activating mTORC1 Signaling.
Role of mitochondrial acyl-CoA dehydrogenases in the metabolism of dicarboxylic fatty acids.
Deciphering the potential involvement of PXMP2 and PEX11B in hydrogen peroxide permeation across the peroxisomal membrane reveals a role for PEX11B in protein sorting.
Differential distribution of peroxisomal proteins points to specific roles of peroxisomes in the murine retina.
Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells.
Differential activities of peroxisomes along the mouse intestinal epithelium.
Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation.
Landowski M, Bhute VJ, Grindel S, Haugstad Z, Gyening YK, Tytanic M, Brush RS, Moyer LJ, Nelson DW, Davis CR, Yen CE, Ikeda S, Agbaga MP, Ikeda A
Communications biology 2023 Jan 4;6(1):8
Communications biology 2023 Jan 4;6(1):8
Germ cell-specific deletion of Pex3 reveals essential roles of PEX3-dependent peroxisomes in spermiogenesis.
Yao Y, Shi B, Zhang X, Wang X, Li S, Yao Y, Guo Y, Chen D, Wang B, Yuan Y, Sha J, Guo X
Journal of biomedical research 2023 Dec 8;38(1):24-36
Journal of biomedical research 2023 Dec 8;38(1):24-36
Cell Type-Selective Loss of Peroxisomal β-Oxidation Impairs Bipolar Cell but Not Photoreceptor Survival in the Retina.
Swinkels D, Das Y, Kocherlakota S, Vinckier S, Wever E, van Kampen AHC, Vaz FM, Baes M
Cells 2022 Jan 4;11(1)
Cells 2022 Jan 4;11(1)
In Situ Peroxidase Labeling Followed by Mass-Spectrometry Reveals TIA1 Interactome.
Gourdomichali O, Zonke K, Kattan FG, Makridakis M, Kontostathi G, Vlahou A, Doxakis E
Biology 2022 Feb 11;11(2)
Biology 2022 Feb 11;11(2)
Quantitative proteomic analysis identified differentially expressed proteins with tail/rump fat deposition in Chinese thin- and fat-tailed lambs.
Han J, Guo T, Yue Y, Lu Z, Liu J, Yuan C, Niu C, Yang M, Yang B
PloS one 2021;16(2):e0246279
PloS one 2021;16(2):e0246279
Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice.
Ranea-Robles P, Portman K, Bender A, Lee K, He JC, Mulholland DJ, Argmann C, Houten SM
Kidney360 2021 Sep;2(9):1441-1454
Kidney360 2021 Sep;2(9):1441-1454
The Peroxisomal Localization of Hsd17b4 Is Regulated by Its Interaction with Phosphatidylserine.
Lee SA, Lee J, Kim K, Moon H, Min C, Moon B, Kim D, Yang S, Park H, Lee G, Park R, Park D
Molecules and cells 2021 Apr 30;44(4):214-222
Molecules and cells 2021 Apr 30;44(4):214-222
WHSC1 Promotes Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma by Activating mTORC1 Signaling.
Dai J, Jiang L, Qiu L, Shao Y, Shi P, Li J
OncoTargets and therapy 2020;13:7033-7044
OncoTargets and therapy 2020;13:7033-7044
Role of mitochondrial acyl-CoA dehydrogenases in the metabolism of dicarboxylic fatty acids.
Bharathi SS, Zhang Y, Gong Z, Muzumdar R, Goetzman ES
Biochemical and biophysical research communications 2020 Jun 18;527(1):162-166
Biochemical and biophysical research communications 2020 Jun 18;527(1):162-166
Deciphering the potential involvement of PXMP2 and PEX11B in hydrogen peroxide permeation across the peroxisomal membrane reveals a role for PEX11B in protein sorting.
Lismont C, Koster J, Provost S, Baes M, Van Veldhoven PP, Waterham HR, Fransen M
Biochimica et biophysica acta. Biomembranes 2019 Oct 1;1861(10):182991
Biochimica et biophysica acta. Biomembranes 2019 Oct 1;1861(10):182991
Differential distribution of peroxisomal proteins points to specific roles of peroxisomes in the murine retina.
Das Y, Roose N, De Groef L, Fransen M, Moons L, Van Veldhoven PP, Baes M
Molecular and cellular biochemistry 2019 Jun;456(1-2):53-62
Molecular and cellular biochemistry 2019 Jun;456(1-2):53-62
Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells.
Nozaki M, Haraguchi S, Miyazaki T, Shigeta D, Kano N, Lei XF, Kim-Kaneyama JR, Minakata H, Miyazaki A, Tsutsui K
Scientific reports 2018 Feb 1;8(1):2167
Scientific reports 2018 Feb 1;8(1):2167
Differential activities of peroxisomes along the mouse intestinal epithelium.
Morvay PL, Baes M, Van Veldhoven PP
Cell biochemistry and function 2017 Apr;35(3):144-155
Cell biochemistry and function 2017 Apr;35(3):144-155
Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation.
Verheijden S, Bottelbergs A, Krysko O, Krysko DV, Beckers L, De Munter S, Van Veldhoven PP, Wyns S, Kulik W, Nave KA, Ramer MS, Carmeliet P, Kassmann CM, Baes M
Neurobiology of disease 2013 Oct;58:258-69
Neurobiology of disease 2013 Oct;58:258-69
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 15116-1-AP(HSD17B4 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using HSD17B4 antibody 15116-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 15116-1-AP(HSD17B4 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 15116-1-AP(HSD17B4 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
