BS7902

antibody from Bioworld Technology, Inc
Targeting: TGM3 TGE
Provider product page for BS7902
Western blot
Immunohistochemistry

Antibody data

Product number
BS7902 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TGM3 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TGM3.
Description
TGases (transglutaminases) catalyze the post-translational modification of proteins by transamidation of available glutamine residues, resulting in a stable, insoluble macromolecular structure. The human haploid genome contains at least five distinct transglutaminases that are differentially expressed in time-space and tissue-specific ways. Epidermal-type TGase (TGase3), also known as TGE, TGX and TGM3, is involved in the formation of the cornified cell envelope by cross-linking a variety of structural proteins in the epidermis. It is expressed during late stages of terminal differentiation of the epidermis and in certain cell types of the hair follicle. TGase3 is widely expressed and is important for epithelial barrier formation. It is a zymogen, requiring proteolysis for activity. TGase3 is devoid of GTPase activity, but its TGase activity is inhibited by GTP as in the case of tissue-type TGase (TGase2).
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TGM3 protein structure - BS7902 shown in red.