ABIN499459

antibody from antibodies-online

Targeting: BICD2 KIAA0699

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN499459

Provider

antibodies-online

Product name

anti-Bicaudal D Homolog 2 (Drosophila) (BICD2) (Center) antibody

Antibody type

Polyclonal

Antigen

BICD2 antibody was raised against a 14 amino acid peptide from near the center of humanBICD2. (ABIN499458)

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

0.1 mg

Storage

Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch.

References

Submitted references

A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice.

Teuling E, van Dis V, Wulf PS, Haasdijk ED, Akhmanova A, Hoogenraad CC, Jaarsma D
Human molecular genetics 2008 Sep 15;17(18):2849-62

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Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2.

Holland PM, Milne A, Garka K, Johnson RS, Willis C, Sims JE, Rauch CT, Bird TA, Virca GD
The Journal of biological chemistry 2002 May 3;277(18):16229-40

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Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes.

Hoogenraad CC, Akhmanova A, Howell SA, Dortland BR, De Zeeuw CI, Willemsen R, Visser P, Grosveld F, Galjart N
The EMBO journal 2001 Aug 1;20(15):4041-54

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Western blot analysis of BICD2 in A549 cell lysate with AP30146PU-N BICD2 antibody at (A) 1 and (B) 2 ?g/ml.