Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- H00051132-B01P - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00051132-B01P, RRID:AB_2181965
- Product name
- Mouse Polyclonal RNF12 Antibody
- Antibody type
- Polyclonal
- Description
- Protein A purified. Reacts with ring finger protein 12.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Pathogenic variants in E3 ubiquitin ligase RLIM/RNF12 lead to a syndromic X-linked intellectual disability and behavior disorder.
REX1 is the critical target of RNF12 in imprinted X chromosome inactivation in mice.
Frints SGM, Ozanturk A, RodrÃguez Criado G, Grasshoff U, de Hoon B, Field M, Manouvrier-Hanu S, E Hickey S, Kammoun M, Gripp KW, Bauer C, Schroeder C, Toutain A, Mihalic Mosher T, Kelly BJ, White P, Dufke A, Rentmeester E, Moon S, Koboldt DC, van Roozendaal KEP, Hu H, Haas SA, Ropers HH, Murray L, Haan E, Shaw M, Carroll R, Friend K, Liebelt J, Hobson L, De Rademaeker M, Geraedts J, Fryns JP, Vermeesch J, Raynaud M, Riess O, Gribnau J, Katsanis N, Devriendt K, Bauer P, Gecz J, Golzio C, Gontan C, Kalscheuer VM
Molecular psychiatry 2019 Nov;24(11):1748-1768
Molecular psychiatry 2019 Nov;24(11):1748-1768
REX1 is the critical target of RNF12 in imprinted X chromosome inactivation in mice.
Gontan C, Mira-Bontenbal H, Magaraki A, Dupont C, Barakat TS, Rentmeester E, Demmers J, Gribnau J
Nature communications 2018 Nov 12;9(1):4752
Nature communications 2018 Nov 12;9(1):4752
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: RNF12 Antibody [H00051132-B01P] - Analysis of RNF12 expression in transfected 293T cell line by RNF12 polyclonal antibody. Lane 1: RNF12 transfected lysate(68.64 KDa). Lane 2: Non-transfected lysate.