abx015995

antibody from Abbexa

Targeting: SMAD6 HsT17432, MADH6, MADH7

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

abx015995

Provider

Abbexa

Product name

Mothers Against Decapentaplegic Homolog 6 (SMAD6) Antibody

Antibody type

Monoclonal

Description

Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1.SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.Binds to regulatory elements in target promoter regions.Tissue specificity: Ubiquitous in various organs, with higher levels in lung.Isoform B is up-regulated in diseased heart tissue.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.