KCNG1

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Multiple alternatively spliced transcript variants have been found in normal and cancerous tissues. [provided by RefSeq, Jul 2008]

Description

Potassium voltage-gated channel modifier subfamily G member 1

Tissue specificity

Tissue enhanced (brain, endometrium)

Subcell location

Vesicles

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Transporters
Voltage-gated ion channels

Chromosome

20 (51003656 - 51023107)

Ensembl ID

ENSG00000026559  (ver. 103.38)

Orthologs

Mouse Kcng1: ENSMUSG00000074575

UniProt

Q9UIX4

neXtProt

NX_Q9UIX4

Human splice variants
Mouse splice variants

Protein structure