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- Antibody Data
- Antigen structure
- References [10]
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- Product number
- 67321-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- USP8 antibody
- Antibody type
- Monoclonal
- Description
- USP8 antibody (Cat. #67321-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1E12E3
- Vial size
- 20ul, 150ul
Submitted references Deubiquitinase USP8 regulates the spindle assembly checkpoint in oocytes.
MGMT upregulation mediates Temozolomide resistance conferred USP5 dependency.
GPR34 Stabilized by Deubiquitinase USP8 Suppresses Ferroptosis of ATC.
Mechanical signal modulates prostate cancer immune escape by USP8-mediated ubiquitination-dependent degradation of PD-L1 and MHC-1.
USP8 inhibits cigarette smoke extract combined with LPS-induced inflammatory response and ER stress by regulating the ABCB1-mediated MAPK signaling pathway in human bronchial epithelial cells.
Exosomes Derived from Tanshinone IIA-Pretreated Umbilical Cord Mesenchymal Stem Cells Repair Traumatic Spinal Cord Injury by miR-223-5p/USP8/NLRP3 Axis.
A heterozygous germline deletion within USP8 causes severe neurodevelopmental delay with multiorgan abnormalities.
Targeting USP8 Inhibits O-GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT.
USP8 positively regulates hepatocellular carcinoma tumorigenesis and confers ferroptosis resistance through β-catenin stabilization.
The ubiquitin-specific protease 8 antagonizes melatonin-induced endocytic degradation of MT(1) receptor to promote lung adenocarcinoma growth.
Zhou 周长银 C, Zhang 张雪 X, Xu 许根露 G, Wang 王慧 H, Ran 冉宇婷 Y, Li 李昂 A, Sun 孙青原 QY, Ou 欧湘红 XH
Science advances 2026 Mar 13;12(11):eaeb2345
Science advances 2026 Mar 13;12(11):eaeb2345
MGMT upregulation mediates Temozolomide resistance conferred USP5 dependency.
Bhardwaj S, Sanjay, Sharma D, Taneja L, Yadav BK, Yadav AK
Scientific reports 2026 Jan 24;16(1):6118
Scientific reports 2026 Jan 24;16(1):6118
GPR34 Stabilized by Deubiquitinase USP8 Suppresses Ferroptosis of ATC.
Yan B, Guo J, Huang M, Li Z, Sun J, Tan H, Lai W, Chang S
Mediators of inflammation 2025;2025:5576056
Mediators of inflammation 2025;2025:5576056
Mechanical signal modulates prostate cancer immune escape by USP8-mediated ubiquitination-dependent degradation of PD-L1 and MHC-1.
Ke ZB, Chen JY, Xue YT, Lin B, Huang Q, Huang XY, Chen DN, Chen SH, Ye XJ, Zheng QS, Wei Y, Xue XY, Xu N
Cell death & disease 2025 May 23;16(1):413
Cell death & disease 2025 May 23;16(1):413
USP8 inhibits cigarette smoke extract combined with LPS-induced inflammatory response and ER stress by regulating the ABCB1-mediated MAPK signaling pathway in human bronchial epithelial cells.
Wang M, Song W, Liu X, Meng A
Journal of inflammation (London, England) 2025 Dec 29;22(1):53
Journal of inflammation (London, England) 2025 Dec 29;22(1):53
Exosomes Derived from Tanshinone IIA-Pretreated Umbilical Cord Mesenchymal Stem Cells Repair Traumatic Spinal Cord Injury by miR-223-5p/USP8/NLRP3 Axis.
Shen G, Liu M, Wang J, Qi Z, Cao Y, Jin Z, Chen S, Wan B, Gu J
ACS applied materials & interfaces 2025 Aug 13;17(32):45511-45526
ACS applied materials & interfaces 2025 Aug 13;17(32):45511-45526
A heterozygous germline deletion within USP8 causes severe neurodevelopmental delay with multiorgan abnormalities.
Sakamoto M, Kurosawa K, Tanoue K, Iwama K, Ishida F, Watanabe Y, Okamoto N, Tsuchida N, Uchiyama Y, Koshimizu E, Fujita A, Misawa K, Miyatake S, Mizuguchi T, Matsumoto N
Journal of human genetics 2024 Feb;69(2):85-90
Journal of human genetics 2024 Feb;69(2):85-90
Targeting USP8 Inhibits O-GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT.
Tang J, Long G, Hu K, Xiao D, Liu S, Xiao L, Zhou L, Tao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(33):e2302953
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(33):e2302953
USP8 positively regulates hepatocellular carcinoma tumorigenesis and confers ferroptosis resistance through β-catenin stabilization.
Tang J, Long G, Xiao L, Zhou L
Cell death & disease 2023 Jun 13;14(6):360
Cell death & disease 2023 Jun 13;14(6):360
The ubiquitin-specific protease 8 antagonizes melatonin-induced endocytic degradation of MT(1) receptor to promote lung adenocarcinoma growth.
Sun Q, Zhang J, Li X, Yang G, Cheng S, Guo D, Zhang Q, Sun F, Zhao F, Yang D, Wang S, Wang T, Liu S, Zou L, Zhang Y, Liu H
Journal of advanced research 2022 Nov;41:1-12
Journal of advanced research 2022 Nov;41:1-12
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