67321-1-Ig

antibody from Proteintech Group

Targeting: USP8 HumORF8, KIAA0055, SPG59, UBPY

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

67321-1-Ig

Provider

Proteintech Group

Product name

USP8 antibody

Antibody type

Monoclonal

Description

USP8 antibody (Cat. #67321-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse and has been validated for the following applications: IF, IHC, WB, ELISA.

Reactivity

Human, Mouse

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1E12E3

Vial size

20ul, 150ul

References

Submitted references

A heterozygous germline deletion within USP8 causes severe neurodevelopmental delay with multiorgan abnormalities.

Sakamoto M, Kurosawa K, Tanoue K, Iwama K, Ishida F, Watanabe Y, Okamoto N, Tsuchida N, Uchiyama Y, Koshimizu E, Fujita A, Misawa K, Miyatake S, Mizuguchi T, Matsumoto N
Journal of human genetics 2024 Feb;69(2):85-90

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Targeting USP8 Inhibits O-GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT.

Tang J, Long G, Hu K, Xiao D, Liu S, Xiao L, Zhou L, Tao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(33):e2302953

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USP8 positively regulates hepatocellular carcinoma tumorigenesis and confers ferroptosis resistance through β-catenin stabilization.

Tang J, Long G, Xiao L, Zhou L
Cell death & disease 2023 Jun 13;14(6):360

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The ubiquitin-specific protease 8 antagonizes melatonin-induced endocytic degradation of MT(1) receptor to promote lung adenocarcinoma growth.

Sun Q, Zhang J, Li X, Yang G, Cheng S, Guo D, Zhang Q, Sun F, Zhao F, Yang D, Wang S, Wang T, Liu S, Zou L, Zhang Y, Liu H
Journal of advanced research 2022 Nov;41:1-12