Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 22624-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- PDE5A antibody
- Antibody type
- Polyclonal
- Description
- PDE5A antibody (Cat. #22624-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Protective Effect of Paeoniae Radix Alba Carbonisata on Hepatic Amyloidosis by Regulating Calcium Homeostasis.
Downregulation of miR-214 promotes dilated Cardiomyopathy Progression through PDE5A-Mediated cGMP regulation.
Exploring the oncogenic role of RGS19 in bladder cancer progression and prognosis.
CircPDE5A-encoded novel regulator of the PI3K/AKT pathway inhibits esophageal squamous cell carcinoma progression by promoting USP14-mediated de-ubiquitination of PIK3IP1.
Exercise training affects calcium ion transport by downregulating the CACNA2D1 protein to reduce hypertension-induced myocardial injury in mice.
Zhenwu decoction ameliorates cardiac hypertrophy through activating sGC (soluble guanylate cyclase) - cGMP (cyclic guanosine monophosphate) - PKG (protein kinase G) pathway.
Identification of potential genes in upper tract urothelial carcinoma using next-generation sequencing with bioinformatics and in vitro analyses.
Myostatin Mutation Promotes Glycolysis by Increasing Phosphorylation of Phosphofructokinase via Activation of PDE5A-cGMP-PKG in Cattle Heart.
Decreased Cyclic Guanosine Monophosphate-Protein Kinase G Signaling Impairs Angiogenesis in a Lamb Model of Persistent Pulmonary Hypertension of the Newborn.
An MRTF-A-Sp1-PDE5 Axis Mediates Angiotensin-II-Induced Cardiomyocyte Hypertrophy.
Augmentation of cGMP/PKG pathway and colonic motility by hydrogen sulfide.
Liu G, Wang Z, Xu H, Jia J, Xue Z, Ge W, Ji X, Cui L, Huang Y
International journal of molecular sciences 2026 Mar 11;27(6)
International journal of molecular sciences 2026 Mar 11;27(6)
Downregulation of miR-214 promotes dilated Cardiomyopathy Progression through PDE5A-Mediated cGMP regulation.
Yan J, Wang X, Cao P, Li Q, Wu H
Scientific reports 2024 Nov 14;14(1):28070
Scientific reports 2024 Nov 14;14(1):28070
Exploring the oncogenic role of RGS19 in bladder cancer progression and prognosis.
Yan L, Luo G, Han C, Meng J, Liang C
Acta histochemica 2024 Dec;126(8):152212
Acta histochemica 2024 Dec;126(8):152212
CircPDE5A-encoded novel regulator of the PI3K/AKT pathway inhibits esophageal squamous cell carcinoma progression by promoting USP14-mediated de-ubiquitination of PIK3IP1.
Lei K, Liang R, Liang J, Lu N, Huang J, Xu K, Tan B, Wang K, Liang Y, Wang W, Lin H, Wang M
Journal of experimental & clinical cancer research : CR 2024 Apr 24;43(1):124
Journal of experimental & clinical cancer research : CR 2024 Apr 24;43(1):124
Exercise training affects calcium ion transport by downregulating the CACNA2D1 protein to reduce hypertension-induced myocardial injury in mice.
Gao S, Yao W, Zhou R, Pei Z
iScience 2024 Apr 19;27(4):109351
iScience 2024 Apr 19;27(4):109351
Zhenwu decoction ameliorates cardiac hypertrophy through activating sGC (soluble guanylate cyclase) - cGMP (cyclic guanosine monophosphate) - PKG (protein kinase G) pathway.
Chen L, Zhou X, Deng Y, Yang Y, Chen X, Chen Q, Liu Y, Fu X, Kwan HY, You Y, Jin W, Zhao X
Journal of ethnopharmacology 2023 Jan 10;300:115705
Journal of ethnopharmacology 2023 Jan 10;300:115705
Identification of potential genes in upper tract urothelial carcinoma using next-generation sequencing with bioinformatics and in vitro analyses.
Lee HY, Li CC, Li WM, Hsu YL, Yeh HC, Ke HL, Yeh BW, Huang CN, Li CF, Kuo PL, Wu WJ
PeerJ 2021;9:e11343
PeerJ 2021;9:e11343
Myostatin Mutation Promotes Glycolysis by Increasing Phosphorylation of Phosphofructokinase via Activation of PDE5A-cGMP-PKG in Cattle Heart.
Gu M, Zhou X, Zhu L, Gao Y, Gao L, Bai C, Yang L, Li G
Frontiers in cell and developmental biology 2021;9:774185
Frontiers in cell and developmental biology 2021;9:774185
Decreased Cyclic Guanosine Monophosphate-Protein Kinase G Signaling Impairs Angiogenesis in a Lamb Model of Persistent Pulmonary Hypertension of the Newborn.
Sharma M, Rana U, Joshi C, Michalkiewicz T, Afolayan A, Parchur A, Joshi A, Teng RJ, Konduri GG
American journal of respiratory cell and molecular biology 2021 Nov;65(5):555-567
American journal of respiratory cell and molecular biology 2021 Nov;65(5):555-567
An MRTF-A-Sp1-PDE5 Axis Mediates Angiotensin-II-Induced Cardiomyocyte Hypertrophy.
Wu T, Wang H, Xin X, Yang J, Hou Y, Fang M, Lu X, Xu Y
Frontiers in cell and developmental biology 2020;8:839
Frontiers in cell and developmental biology 2020;8:839
Augmentation of cGMP/PKG pathway and colonic motility by hydrogen sulfide.
Nalli AD, Bhattacharya S, Wang H, Kendig DM, Grider JR, Murthy KS
American journal of physiology. Gastrointestinal and liver physiology 2017 Oct 1;313(4):G330-G341
American journal of physiology. Gastrointestinal and liver physiology 2017 Oct 1;313(4):G330-G341
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The PDE5A antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PDE5A. This antibody recognizes human, mouse antigen. The PDE5A antibody has been validated for the following applications: ELISA, WB analysis.