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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA020376 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA020376, RRID:AB_1855867
- Product name
- Anti-PSPH
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human PSPH, Gene description: phosphoserine phosphatase, Alternative Gene Names: PSP, Validated applications: WB, IHC, Uniprot ID: P78330, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references p63 orchestrates serine and one carbon metabolism enzymes expression in head and neck cancer
Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis
Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers.
In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
Analysis of plasma metabolic profile, characteristics and enzymes in the progression from chronic hepatitis B to hepatocellular carcinoma
Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
Cappello A, Tosetti G, Smirnov A, Ganini C, Yang X, Shi Y, Wang Y, Melino G, Bernassola F, Candi E
Biology Direct 2023;18(1)
Biology Direct 2023;18(1)
Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis
Kiweler N, Delbrouck C, Pozdeev V, Neises L, Soriano-Baguet L, Eiden K, Xian F, Benzarti M, Haase L, Koncina E, Schmoetten M, Jaeger C, Noman M, Vazquez A, Janji B, Dittmar G, Brenner D, Letellier E, Meiser J
Nature Communications 2022;13(1)
Nature Communications 2022;13(1)
Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers.
Van Nyen T, Planque M, van Wagensveld L, Duarte JAG, Zaal EA, Talebi A, Rossi M, Körner PR, Rizzotto L, Moens S, De Wispelaere W, Baiden-Amissah REM, Sonke GS, Horlings HM, Eelen G, Berardi E, Swinnen JV, Berkers CR, Carmeliet P, Lambrechts D, Davidson B, Agami R, Fendt SM, Annibali D, Amant F
Nature communications 2022 Aug 5;13(1):4578
Nature communications 2022 Aug 5;13(1):4578
In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
Rinaldi G, Pranzini E, Van Elsen J, Broekaert D, Funk C, Planque M, Doglioni G, Altea-Manzano P, Rossi M, Geldhof V, Teoh S, Ross C, Hunter K, Lunt S, Grünewald T, Fendt S
Molecular Cell 2021;81(2):386-397.e7
Molecular Cell 2021;81(2):386-397.e7
Analysis of plasma metabolic profile, characteristics and enzymes in the progression from chronic hepatitis B to hepatocellular carcinoma
Cai F, Song Y, Lu Y, Zhang Y, Hu Y, Su S
Aging 2020;12(14):14949-14965
Aging 2020;12(14):14949-14965
Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors
Kitazawa S, Ebara S, Ando A, Baba Y, Satomi Y, Soga T, Hara T
Oncotarget 2017;8(17):28922-28938
Oncotarget 2017;8(17):28922-28938
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor
Krall A, Xu S, Graeber T, Braas D, Christofk H
Nature Communications 2016;7(1)
Nature Communications 2016;7(1)
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
Possemato R, Marks K, Shaul Y, Pacold M, Kim D, Birsoy K, Sethumadhavan S, Woo H, Jang H, Jha A, Chen W, Barrett F, Stransky N, Tsun Z, Cowley G, Barretina J, Kalaany N, Hsu P, Ottina K, Chan A, Yuan B, Garraway L, Root D, Mino-Kenudson M, Brachtel E, Driggers E, Sabatini D
Nature 2011;476(7360):346-350
Nature 2011;476(7360):346-350
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human fallopian tube and skeletal muscle tissues using HPA020376 antibody. Corresponding PSPH RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
