27426-1-AP

antibody from Proteintech Group

Targeting: NPPA ANP, PND

Provider product page for 27426-1-AP

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Product number: 27426-1-AP - Provider product page
Provider: Proteintech Group
Product name: NPPA antibody
Antibody type: Polyclonal
Description: NPPA antibody (Cat. #27426-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

NPPA protein structure - 27426-1-AP shown in red.

Submitted references The mechanisms and therapeutic potential of clopidogrel in mitigating diabetic cardiomyopathy in db/db mice.

Li B, Zhang Y, Zheng Y, Cai H
iScience 2024 Mar 15;27(3):109134

MCT4-dependent lactate transport: a novel mechanism for cardiac energy metabolism injury and inflammation in type 2 diabetes mellitus.

Ma XM, Geng K, Wang P, Jiang Z, Law BY, Xu Y
Cardiovascular diabetology 2024 Mar 14;23(1):96

The total xanthones extracted from Gentianella acuta alleviates HFpEF by activating the IRE1α/Xbp1s pathway.

Zhao L, Qin Y, Liu Y, An L, Liu W, Zhang C, Song Q, Dai C, Zhang J, Li A
Journal of cellular and molecular medicine 2024 Jun;28(11):e18466

Lycorine inhibits Ang II-induced heart remodeling and inflammation by suppressing the PI3K-AKT/NF-κB pathway.

Tuo P, Zhao R, Li N, Yan S, Yang G, Wang C, Sun J, Sun H, Wang M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155464

Overexpression of macrophage migration inhibitory factor protects against pressure overload-induced cardiac hypertrophy through regulating the miR-29b-3p/HBP1 axis.

Wen L, Chen W, Zhu C, Li J, Zhou J, Zhang M, Zhang W, Xue Q
Physiological reports 2024 Jun;12(12):e16022

Carnosol attenuates angiotensin II-induced cardiac remodeling and inflammation via directly binding to p38 and inhibiting p38 activation.

Xu D, Ye B, Lin L, Jin Y, Jiang Y, Zheng Z, Chen Y, Han X, Wang W, Wu G, Zhuang Z, Shan P, Liang G
International immunopharmacology 2024 Jun 15;134:112143

PKD knockdown mitigates Ang II-induced cardiac hypertrophy and ferroptosis via the JNK/P53 signaling pathway.

Lv C, Zhou L, Meng Y, Yuan H, Geng J
Cellular signalling 2024 Jan;113:110974

CTRP3 alleviates mitochondrial dysfunction and oxidative stress injury in pathological cardiac hypertrophy by activating UPRmt via the SIRT1/ATF5 axis.

Shi L, Tan Y, Zheng W, Cao G, Zhou H, Li P, Cui J, Song Y, Feng L, Li H, Shan W, Zhang B, Yi W
Cell death discovery 2024 Jan 26;10(1):53

JOSD2 mediates isoprenaline-induced heart failure by deubiquitinating CaMKIIδ in cardiomyocytes.

Xu J, Liang S, Wang Q, Zheng Q, Wang M, Qian J, Yu T, Lou S, Luo W, Zhou H, Liang G
Cellular and molecular life sciences : CMLS 2024 Jan 10;81(1):18

Exercise training affects calcium ion transport by downregulating the CACNA2D1 protein to reduce hypertension-induced myocardial injury in mice.

Gao S, Yao W, Zhou R, Pei Z
iScience 2024 Apr 19;27(4):109351

Identification of diagnostic immune-related gene biomarkers for predicting heart failure after acute myocardial infarction.

Hu Y, Chen X, Mei X, Luo Z, Wu H, Zhang H, Zeng Q, Ren H, Xu D
Open medicine (Warsaw, Poland) 2023;18(1):20230878

Dapagliflozin attenuates myocardial hypertrophy via activating the SIRT1/HIF-1α signaling pathway.

Yang J, Li L, Zheng X, Lu Z, Zhou H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115125

Chronic β-adrenergic stress contributes to cardiomyopathy in rodents with collagen-induced arthritis.

Zhu ZD, Zhang M, Wang Z, Jiang CR, Huang CJ, Cheng HJ, Guan QY, Su TT, Wang MM, Gao Y, Wu HF, Wei W, Han YS, Wang QT
Acta pharmacologica Sinica 2023 Oct;44(10):1989-2003

SOX4 as a potential therapeutic target for pathological cardiac hypertrophy.

Bin S, Xinyi F, Huan P, Xiaoqin Z, Jiming W, Yi H, Ziyue L, Xiaochun Z, Zhouqi L, Bangwei Z, Jing J, Shihui L, Jinlai G
European journal of pharmacology 2023 Nov 5;958:176071

CD9 exacerbates pathological cardiac hypertrophy through regulating GP130/STAT3 signaling pathway.

Li Y, Fan S, Kong L, Hao Z, Zhou Y, Shangguan J, Gao L, Wang M, Kang Y, Li X, Huang K, Zhang C, Liu Z
iScience 2023 Nov 17;26(11):108070

GLUT4 mediates the protective function of gastrodin against pressure overload-induced cardiac hypertrophy.

Zhang M, Tan Y, Song Y, Zhu M, Zhang B, Chen C, Liu Y, Shi L, Cui J, Shan W, Jia Z, Feng L, Cao G, Yi W, Sun Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114324

HypERlnc attenuates angiotensin II-induced cardiomyocyte hypertrophy via promoting SIRT1 SUMOylation-mediated activation of PGC-1α/PPARα pathway in AC16 cells.

Yue L, Sheng S, Yuan M, Lu J, Li T, Shi Y, Dong Z
Cell biology international 2023 Jun;47(6):1068-1080

Trim65 attenuates isoproterenol-induced cardiac hypertrophy by promoting autophagy and ameliorating mitochondrial dysfunction via the Jak1/Stat1 signaling pathway.

Liu H, Zhou Z, Deng H, Tian Z, Wu Z, Liu X, Ren Z, Jiang Z
European journal of pharmacology 2023 Jun 15;949:175735

Exploring novel biomarkers in dilated cardiomyopathy‑induced heart failure by integrated analysis and in vitro experiments.

Zhou L, Peng F, Li J, Gong H
Experimental and therapeutic medicine 2023 Jul;26(1):325

G9a inhibition promotes the formation of pacemaker-like cells by reducing the enrichment of H3K9me2 in the HCN4 promoter region.

Xu P, Jin K, Zhou J, Gu J, Gu X, Dong L, Sun X
Molecular medicine reports 2023 Feb;27(2)

Muscone inhibits angiotensin II-induced cardiac hypertrophy through the STAT3, MAPK and TGF-β/SMAD signaling pathways.

Liu YJ, Xu JJ, Yang C, Li YL, Chen MW, Liu SX, Zheng XH, Luo P, Li R, Xiao D, Shan ZG
Molecular biology reports 2023 Dec 29;51(1):39

Soluble epoxide hydrolase and TRPC3 channels jointly contribute to homocysteine-induced cardiac hypertrophy: Interrelation and regulation by C/EBPβ.

Zhou Y, Wang XC, Wei JH, Xue HM, Sun WT, He GW, Yang Q
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166643

Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function.

Ma Z, Liu Z, Li X, Zhang H, Han D, Xiong W, Zhou H, Yang X, Zeng Q, Ren H, Xu D
Biology 2023 Apr 11;12(4)

SUMOylation of SIRT1 activating PGC-1α/PPARα pathway mediates the protective effect of LncRNA-MHRT in cardiac hypertrophy.

Liu MY, Yue LJ, Luo YC, Lu J, Wu GD, Sheng SQ, Shi YQ, Dong ZX
European journal of pharmacology 2022 Sep 5;930:175155

Transient Receptor Potential Vanilloid Type 1 Protects Against Pressure Overload-Induced Cardiac Hypertrophy by Promoting Mitochondria-Associated Endoplasmic Reticulum Membranes.

Wang Y, Li X, Xu X, Qu X, Yang Y
Journal of cardiovascular pharmacology 2022 Sep 1;80(3):430-441

Overexpression of cytosolic long noncoding RNA cytb protects against pressure-overload-induced heart failure via sponging microRNA-103-3p.

Zhang X, Yuan S, Liu J, Tang Y, Wang Y, Zhan J, Fan J, Nie X, Zhao Y, Wen Z, Li H, Chen C, Wang DW
Molecular therapy. Nucleic acids 2022 Mar 8;27:1127-1145

Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation.

Li X, Zhang Y, Zhao Y, Zhou Y, Han Q, Yang Y, Zhang L, Shi L, Jin X, Zhang R, Gao H, Xue G, Li D, Zhang ZR, Lu Y, Yang B, Pan Z
Pharmacological research 2022 Aug;182:106284

Gastrodin Exerts Cardioprotective Action via Inhibition of Insulin-Like Growth Factor Type 2/Insulin-Like Growth Factor Type 2 Receptor Expression in Cardiac Hypertrophy.

Lu J, Ma X, Gao WC, Zhang X, Fu Y, Liu Q, Tian L, Qin XD, Yang W, Zheng HY, Zheng CB
ACS omega 2021 Jul 6;6(26):16763-16774

CBL aggravates Ang II-induced cardiac hypertrophy via the VHL/HIF-1α pathway.

Yang Y, Zou P, He L, Shao J, Tang Y, Li J
Experimental cell research 2021 Aug 15;405(2):112730

Pygo1 regulates pathological cardiac hypertrophy via a β-catenin-dependent mechanism.

Lin L, Xu W, Li Y, Zhu P, Yuan W, Liu M, Shi Y, Chen Y, Liang J, Chen J, Yang B, Cai W, Wen Y, Zhu X, Peng X, Zhou Z, Mo X, Wan Y, Yuan H, Li F, Ye X, Jiang Z, Wang Y, Zhuang J, Fan X, Wu X
American journal of physiology. Heart and circulatory physiology 2021 Apr 1;320(4):H1634-H1645

Examination of the Effect of a 50-Hz Electromagnetic Field at 500 μT on Parameters Related With the Cardiovascular System in Rats.

Zhang Y, Li L, Liu X, Ding L, Wu X, Wang J, He M, Hou H, Ruan G, Lai J, Chen C
Frontiers in public health 2020;8:87

Ranolazine prevents pressure overload-induced cardiac hypertrophy and heart failure by restoring aberrant Na(+) and Ca(2+) handling.

Nie J, Duan Q, He M, Li X, Wang B, Zhou C, Wu L, Wen Z, Chen C, Wang DW, Alsina KM, Wehrens XHT, Wang DW, Ni L
Journal of cellular physiology 2019 Jul;234(7):11587-11601

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