Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 19544-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19544-1-AP, RRID:AB_10644294
- Product name
- FEM1B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FEM1B antibody (Cat. #19544-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TOM20-driven E3 ligase recruitment regulates mitochondrial dynamics through PLD6.
Reactive oxygen species control protein degradation at the mitochondrial import gate.
Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications.
Structural basis and regulation of the reductive stress response.
A Cellular Mechanism to Detect and Alleviate Reductive Stress.
Raiff A, Zhao S, Bekturova A, Zenge C, Mazor S, Chen X, Ru W, Makaros Y, Ast T, Ordureau A, Xu C, Koren I
Nature chemical biology 2026 Jan;22(1):37-47
Nature chemical biology 2026 Jan;22(1):37-47
Reactive oxygen species control protein degradation at the mitochondrial import gate.
McMinimy R, Manford AG, Gee CL, Chandrasekhar S, Mousa GA, Chuang J, Phu L, Shih KY, Rose CM, Kuriyan J, Bingol B, Rapé M
Molecular cell 2024 Dec 5;84(23):4612-4628.e13
Molecular cell 2024 Dec 5;84(23):4612-4628.e13
Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications.
Henning NJ, Manford AG, Spradlin JN, Brittain SM, Zhang E, McKenna JM, Tallarico JA, Schirle M, Rape M, Nomura DK
Journal of the American Chemical Society 2022 Jan 19;144(2):701-708
Journal of the American Chemical Society 2022 Jan 19;144(2):701-708
Structural basis and regulation of the reductive stress response.
Manford AG, Mena EL, Shih KY, Gee CL, McMinimy R, Martínez-González B, Sherriff R, Lew B, Zoltek M, Rodríguez-Pérez F, Woldesenbet M, Kuriyan J, Rape M
Cell 2021 Oct 14;184(21):5375-5390.e16
Cell 2021 Oct 14;184(21):5375-5390.e16
A Cellular Mechanism to Detect and Alleviate Reductive Stress.
Manford AG, Rodríguez-Pérez F, Shih KY, Shi Z, Berdan CA, Choe M, Titov DV, Nomura DK, Rape M
Cell 2020 Oct 1;183(1):46-61.e21
Cell 2020 Oct 1;183(1):46-61.e21
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The FEM1B antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human FEM1B. This antibody recognizes human, mouse, rat antigen. The FEM1B antibody has been validated for the following applications: ELISA, WB analysis.