RA0444

antibody from Oursmab

Targeting: KIT C-Kit, CD117, PBT, SCFR

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0444

Provider

Oursmab

Product name

Briquilimab (Biosimilar Reference Antibody) (KIT)

Antibody type

Monoclonal

Description

Briquilimab (formerly known as JSP191) is a monoclonal antibody in clinical development as a conditioning agent for stem cell transplants and gene therapies. It works by selectively depleting blood-forming stem cells in the bone marrow to create space for new, healthy donor or gene-corrected stem cells to engraft. Unlike traditional chemotherapy- or radiation-based conditioning, Briquilimab is designed to be more targeted. It achieved an important milestone by being granted Breakthrough Therapy Designation by the U.S. FDA in 2023 for use in patients with severe combined immunodeficiency (SCID) undergoing stem cell transplantation.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.