Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 10330-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10330-1-AP, RRID:AB_2221279
- Product name
- Zyxin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Zyxin antibody (Cat. #10330-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress.
Altered chaperone-nonmuscle myosin II interactions drive pathogenicity of the UNC45A c.710T>C variant in osteo-oto-hepato-enteric syndrome.
Does rAj-Tspin, a novel peptide from A. japonicus, exert antihepatocellular carcinoma effects via the ITGB1/ZYX/FAK/AKT signaling pathway?
Zyxin Inhibits the Proliferation, Migration, and Invasion of Osteosarcoma via Rap1-Mediated Inhibition of the MEK/ERK Signaling Pathway.
O-GlcNAc transferase promotes the nuclear localization of the focal adhesion-associated protein Zyxin to regulate UV-induced cell death.
Essential role of zyxin in platelet biogenesis and glycoprotein Ib-IX surface expression.
Zyxin-involved actin regulation is essential in the maintenance of vinculin focal adhesion and chondrocyte differentiation status.
The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration.
Lasp1 gene disruption is linked to enhanced cell migration and tumor formation.
Targeted disruption of the Lasp-1 gene is linked to increases in histamine-stimulated gastric HCl secretion.
Mayca-Pozo F, Butts SM, Schaefer AW, Montagna C, Spiliotis ET
bioRxiv : the preprint server for biology 2026 Jan 21;
bioRxiv : the preprint server for biology 2026 Jan 21;
Altered chaperone-nonmuscle myosin II interactions drive pathogenicity of the UNC45A c.710T>C variant in osteo-oto-hepato-enteric syndrome.
Waich S, Kreidl K, Vodopiutz J, Demir AM, Pollio AR, Dostál V, Pfaller K, Parlato M, Cerf-Bensussan N, Adam R, Vogel GF, Uhlig HH, Ruemmele FM, Müller T, Hess MW, Janecke AR, Huber LA, Valovka T
JCI insight 2025 Mar 24;10(6)
JCI insight 2025 Mar 24;10(6)
Does rAj-Tspin, a novel peptide from A. japonicus, exert antihepatocellular carcinoma effects via the ITGB1/ZYX/FAK/AKT signaling pathway?
Che Y, Lu X, Wang X, Liu Z, Guan L, Li X, Du Z, Ren H, Wang J, Zhou Z, Lv L
Cancer cell international 2024 Aug 14;24(1):290
Cancer cell international 2024 Aug 14;24(1):290
Zyxin Inhibits the Proliferation, Migration, and Invasion of Osteosarcoma via Rap1-Mediated Inhibition of the MEK/ERK Signaling Pathway.
Wei Z, Xia K, Zhou B, Zheng D, Guo W
Biomedicines 2023 Aug 21;11(8)
Biomedicines 2023 Aug 21;11(8)
O-GlcNAc transferase promotes the nuclear localization of the focal adhesion-associated protein Zyxin to regulate UV-induced cell death.
Zhao Y, Yue S, Zhou X, Guo J, Ma S, Chen Q
The Journal of biological chemistry 2022 Apr;298(4):101776
The Journal of biological chemistry 2022 Apr;298(4):101776
Essential role of zyxin in platelet biogenesis and glycoprotein Ib-IX surface expression.
Yan R, Ge X, Pang N, Ye H, Yuan L, Cheng B, Zhou K, Yang M, Sun Y, Zhang S, Ding Z, Luo J, Ruan C, Dai K
Cell death & disease 2021 Oct 16;12(11):955
Cell death & disease 2021 Oct 16;12(11):955
Zyxin-involved actin regulation is essential in the maintenance of vinculin focal adhesion and chondrocyte differentiation status.
Li G, Song X, Li R, Sun L, Gong X, Chen C, Yang L
Cell proliferation 2019 Jan;52(1):e12532
Cell proliferation 2019 Jan;52(1):e12532
The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration.
Schiefermeier N, Scheffler JM, de Araujo ME, Stasyk T, Yordanov T, Ebner HL, Offterdinger M, Munck S, Hess MW, Wickström SA, Lange A, Wunderlich W, Fässler R, Teis D, Huber LA
The Journal of cell biology 2014 May 26;205(4):525-40
The Journal of cell biology 2014 May 26;205(4):525-40
Lasp1 gene disruption is linked to enhanced cell migration and tumor formation.
Zhang H, Chen X, Bollag WB, Bollag RJ, Sheehan DJ, Chew CS
Physiological genomics 2009 Aug 7;38(3):372-85
Physiological genomics 2009 Aug 7;38(3):372-85
Targeted disruption of the Lasp-1 gene is linked to increases in histamine-stimulated gastric HCl secretion.
Chew CS, Chen X, Bollag RJ, Isales C, Ding KH, Zhang H
American journal of physiology. Gastrointestinal and liver physiology 2008 Jul;295(1):G37-G44
American journal of physiology. Gastrointestinal and liver physiology 2008 Jul;295(1):G37-G44
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Zyxin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Zyxin. This antibody recognizes human antigen. The Zyxin antibody has been validated for the following applications: ELISA, WB analysis.
