Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10330-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10330-1-AP, RRID:AB_2221279
- Product name
- Zyxin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Zyxin antibody (Cat. #10330-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Zyxin Inhibits the Proliferation, Migration, and Invasion of Osteosarcoma via Rap1-Mediated Inhibition of the MEK/ERK Signaling Pathway.
O-GlcNAc transferase promotes the nuclear localization of the focal adhesion-associated protein Zyxin to regulate UV-induced cell death.
Essential role of zyxin in platelet biogenesis and glycoprotein Ib-IX surface expression.
Zyxin-involved actin regulation is essential in the maintenance of vinculin focal adhesion and chondrocyte differentiation status.
The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration.
Lasp1 gene disruption is linked to enhanced cell migration and tumor formation.
Targeted disruption of the Lasp-1 gene is linked to increases in histamine-stimulated gastric HCl secretion.
Wei Z, Xia K, Zhou B, Zheng D, Guo W
Biomedicines 2023 Aug 21;11(8)
Biomedicines 2023 Aug 21;11(8)
O-GlcNAc transferase promotes the nuclear localization of the focal adhesion-associated protein Zyxin to regulate UV-induced cell death.
Zhao Y, Yue S, Zhou X, Guo J, Ma S, Chen Q
The Journal of biological chemistry 2022 Apr;298(4):101776
The Journal of biological chemistry 2022 Apr;298(4):101776
Essential role of zyxin in platelet biogenesis and glycoprotein Ib-IX surface expression.
Yan R, Ge X, Pang N, Ye H, Yuan L, Cheng B, Zhou K, Yang M, Sun Y, Zhang S, Ding Z, Luo J, Ruan C, Dai K
Cell death & disease 2021 Oct 16;12(11):955
Cell death & disease 2021 Oct 16;12(11):955
Zyxin-involved actin regulation is essential in the maintenance of vinculin focal adhesion and chondrocyte differentiation status.
Li G, Song X, Li R, Sun L, Gong X, Chen C, Yang L
Cell proliferation 2019 Jan;52(1):e12532
Cell proliferation 2019 Jan;52(1):e12532
The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration.
Schiefermeier N, Scheffler JM, de Araujo ME, Stasyk T, Yordanov T, Ebner HL, Offterdinger M, Munck S, Hess MW, Wickström SA, Lange A, Wunderlich W, Fässler R, Teis D, Huber LA
The Journal of cell biology 2014 May 26;205(4):525-40
The Journal of cell biology 2014 May 26;205(4):525-40
Lasp1 gene disruption is linked to enhanced cell migration and tumor formation.
Zhang H, Chen X, Bollag WB, Bollag RJ, Sheehan DJ, Chew CS
Physiological genomics 2009 Aug 7;38(3):372-85
Physiological genomics 2009 Aug 7;38(3):372-85
Targeted disruption of the Lasp-1 gene is linked to increases in histamine-stimulated gastric HCl secretion.
Chew CS, Chen X, Bollag RJ, Isales C, Ding KH, Zhang H
American journal of physiology. Gastrointestinal and liver physiology 2008 Jul;295(1):G37-G44
American journal of physiology. Gastrointestinal and liver physiology 2008 Jul;295(1):G37-G44
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Zyxin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Zyxin. This antibody recognizes human antigen. The Zyxin antibody has been validated for the following applications: ELISA, WB analysis.