Tissue expression
Cell line expression
Protein structure

COL6A3

Collagen type VI alpha 3 chain
 
This gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains. This difference in size is largely due to an increase in the number of subdomains, similar to von Willebrand Factor type A domains, that are found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy, a rare autosomal dominant proximal myopathy with early childhood onset. Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy, also referred to as Ullrich scleroatonic muscular dystrophy, an autosomal recessive congenital myopathy that is more severe than Bethlem myopathy. Multiple transcript variants have been identified, but the full-length nature of only some of these variants has been described. [provided by RefSeq, Jun 2009]
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107 antibodies from 19 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Biorbyt
17 antibodies
Abnova Corporation
1 antibody
antibodies-online
16 antibodies
Cusabio Biotech Co., Ltd
2 antibodies
Aviva Systems Biology
1 antibody
Invitrogen Antibodies
5 antibodies
Novus Biologicals
21 antibodies
Atlas Antibodies
1 antibody
OriGene
1 antibody
Boster Biological Technology
1 antibody
St John's Laboratory
1 antibody
Creative Biolabs
2 antibodies
Abbexa
3 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Creative Diagnostics
1 antibody
Proteintech Group
1 antibody
MyBioSource
1 antibody