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Learn20253-1-AP
antibody from Proteintech Group
Targeting: IGF2R
CD222, CI-M6PR, CI-MPR, CIMPR, M6P-R, MPR1, MPR300, MPRI
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 20253-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20253-1-AP, RRID:AB_10859779
- Product name
- IGF2R-Specific antibody
- Antibody type
- Polyclonal
- Description
- IGF2R-Specific antibody (Cat. #20253-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification and Validation of Novel Metastasis-Related Immune Gene Signature in Breast Cancer.
SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion.
Blocking the interaction between circTNRC18 and LIN28A promotes trophoblast epithelial-mesenchymal transformation and alleviates preeclampsia.
Large-Scale CRISPR Screen of LDLR Pathogenic Variants.
Synchronized proinsulin trafficking reveals delayed Golgi export accompanies β-cell secretory dysfunction in rodent models of hyperglycemia.
Nonenzymatic function of DPP4 promotes diabetes-associated cognitive dysfunction through IGF-2R/PKA/SP1/ERp29/IP3R2 pathway-mediated impairment of Treg function and M1 microglia polarization.
A proteomic signature and potential pharmacological opportunities in the adaptive resistance to MEK and PI3K kinase inhibition in pancreatic cancer cells.
Proteomics analysis of cancer tissues identifies IGF2R as a potential therapeutic target in laryngeal carcinoma.
GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway.
Identification and characterization of a membrane receptor that binds to human STC1.
Liquid-liquid phase separation facilitates the biogenesis of secretory storage granules.
Trop2 binding IGF2R induces gefitinib resistance in NSCLC by remodeling the tumor microenvironment.
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
Grandmaternal betaine supplementation enhances hepatic IGF2 expression in F2 rat offspring through modification of promoter DNA methylation.
Rumen-Protected Glucose Stimulates the Insulin-Like Growth Factor System and mTOR/AKT Pathway in the Endometrium of Early Postpartum Dairy Cows.
Hydrogen peroxide induces Arl1 degradation and impairs Golgi-mediated trafficking.
Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams.
Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes.
Ma S, Hao R, Lu YW, Wang HP, Hu J, Qi YX
Breast cancer (Dove Medical Press) 2024;16:199-219
Breast cancer (Dove Medical Press) 2024;16:199-219
SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion.
Zhang J, Kennedy A, de Melo Jorge DM, Xing L, Reid W, Bui S, Joppich J, Rose M, Ercan S, Tang Q, Tai AW, Wang Y
bioRxiv : the preprint server for biology 2024 Mar 15;
bioRxiv : the preprint server for biology 2024 Mar 15;
Blocking the interaction between circTNRC18 and LIN28A promotes trophoblast epithelial-mesenchymal transformation and alleviates preeclampsia.
Chen LL, Li YQ, Kang ZH, Zhang X, Gu SY, Wang N, Shen XY
Molecular and cellular endocrinology 2024 Jan 1;579:112073
Molecular and cellular endocrinology 2024 Jan 1;579:112073
Large-Scale CRISPR Screen of LDLR Pathogenic Variants.
Li M, Ma L, Chen Y, Li J, Wang Y, You W, Yuan H, Tang X, Ouyang H, Pang D
Research (Washington, D.C.) 2023;6:0203
Research (Washington, D.C.) 2023;6:0203
Synchronized proinsulin trafficking reveals delayed Golgi export accompanies β-cell secretory dysfunction in rodent models of hyperglycemia.
Boyer CK, Bauchle CJ, Zhang J, Wang Y, Stephens SB
Scientific reports 2023 Mar 30;13(1):5218
Scientific reports 2023 Mar 30;13(1):5218
Nonenzymatic function of DPP4 promotes diabetes-associated cognitive dysfunction through IGF-2R/PKA/SP1/ERp29/IP3R2 pathway-mediated impairment of Treg function and M1 microglia polarization.
Hui Y, Xu Z, Li J, Kuang L, Zhong Y, Tang Y, Wei J, Zhou H, Zheng T
Metabolism: clinical and experimental 2023 Jan;138:155340
Metabolism: clinical and experimental 2023 Jan;138:155340
A proteomic signature and potential pharmacological opportunities in the adaptive resistance to MEK and PI3K kinase inhibition in pancreatic cancer cells.
Aguilar-Valdés A, González-Vela F, Sánchez-Vidal H, Martínez-Aguilar J
Proteomics 2023 Aug;23(16):e2300041
Proteomics 2023 Aug;23(16):e2300041
Proteomics analysis of cancer tissues identifies IGF2R as a potential therapeutic target in laryngeal carcinoma.
Liu B, Hu Y, Wan L, Wang L, Cheng L, Sun H, Liu Y, Wu D, Zhu J, Hong X, Li Y, Zhou C
Frontiers in endocrinology 2022;13:1031210
Frontiers in endocrinology 2022;13:1031210
GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway.
Zhang W, Yang X, Li Y, Yu L, Zhang B, Zhang J, Cho WJ, Venkatarangan V, Chen L, Burugula BB, Bui S, Wang Y, Duan C, Kitzman JO, Li M
Nature communications 2022 Sep 12;13(1):5351
Nature communications 2022 Sep 12;13(1):5351
Identification and characterization of a membrane receptor that binds to human STC1.
Wan HT, Ng AH, Lee WK, Shi F, Wong CK
Life science alliance 2022 Nov;5(11)
Life science alliance 2022 Nov;5(11)
Liquid-liquid phase separation facilitates the biogenesis of secretory storage granules.
Parchure A, Tian M, Stalder D, Boyer CK, Bearrows SC, Rohli KE, Zhang J, Rivera-Molina F, Ramazanov BR, Mahata SK, Wang Y, Stephens SB, Gershlick DC, von Blume J
The Journal of cell biology 2022 Dec 5;221(12)
The Journal of cell biology 2022 Dec 5;221(12)
Trop2 binding IGF2R induces gefitinib resistance in NSCLC by remodeling the tumor microenvironment.
Sun X, Jia L, Wang T, Zhang Y, Zhao W, Wang X, Chen H
Journal of Cancer 2021;12(17):5310-5319
Journal of Cancer 2021;12(17):5310-5319
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
Zhang Z, Mou Z, Xu C, Wu S, Dai X, Chen X, Ou Y, Chen Y, Yang C, Jiang H
Cell death & disease 2021 Aug 7;12(8):778
Cell death & disease 2021 Aug 7;12(8):778
Grandmaternal betaine supplementation enhances hepatic IGF2 expression in F2 rat offspring through modification of promoter DNA methylation.
Yang S, Zhao N, Sun B, Yang Y, Hu Y, Zhao R
Journal of the science of food and agriculture 2020 Mar 15;100(4):1486-1494
Journal of the science of food and agriculture 2020 Mar 15;100(4):1486-1494
Rumen-Protected Glucose Stimulates the Insulin-Like Growth Factor System and mTOR/AKT Pathway in the Endometrium of Early Postpartum Dairy Cows.
Wang Y, Han X, Tan Z, Kang J, Wang Z
Animals : an open access journal from MDPI 2020 Feb 23;10(2)
Animals : an open access journal from MDPI 2020 Feb 23;10(2)
Hydrogen peroxide induces Arl1 degradation and impairs Golgi-mediated trafficking.
Ireland SC, Huang H, Zhang J, Li J, Wang Y
Molecular biology of the cell 2020 Aug 1;31(17):1931-1942
Molecular biology of the cell 2020 Aug 1;31(17):1931-1942
Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams.
Yang S, Zhao N, Yang Y, Hu Y, Dong H, Zhao R
Journal of agricultural and food chemistry 2018 Mar 21;66(11):2704-2713
Journal of agricultural and food chemistry 2018 Mar 21;66(11):2704-2713
Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes.
Tanaka Y, Suzuki G, Matsuwaki T, Hosokawa M, Serrano G, Beach TG, Yamanouchi K, Hasegawa M, Nishihara M
Human molecular genetics 2017 Mar 1;26(5):969-988
Human molecular genetics 2017 Mar 1;26(5):969-988
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 20253-1-AP(IGF2R-Specific antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IGF2R-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human IGF2R-Specific. This antibody recognizes human antigen. The IGF2R-Specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.
