22151-1-AP

antibody from Proteintech Group

Targeting: TRIM72 MG53

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

22151-1-AP

Provider

Proteintech Group

Product name

TRIM72 antibody

Antibody type

Polyclonal

Description

TRIM72 antibody (Cat. #22151-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

MG53 protects against septic cardiac dysfunction by ubiquitinating ATF2.

Tian M, Shi Y, Gong X, Tan W, Guo X, Chen Y, Yang P, Ren H, Cai Q, Ma J, Zeng C, Wu G
Journal of advanced research 2026 Jan;79:263-275

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MG53 mediates skeletal muscle-liver cross-talk and enhances alcohol metabolism in alcoholic liver disease.

Shu T, Zeng X, Wang J, Jiang H, Wang Y, Zhang M, Jiang L, He B, Yang L, Liu N, Tang M, Jiang Y, Zhang L, Chen P, Xie J, Fang D, Lee KE, Chen Y, Kim J, Liu R, Ye Y, Han Y, Ma J, Zeng C
Nature communications 2026 Feb 13;17(1)

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Mitochondria-encoded peptide MOTS-c participates in plasma membrane repair by facilitating the translocation of TRIM72 to membrane.

Jia H, Zhou LC, Chen YF, Zhang W, Qi W, Wang P, Huang X, Guo JW, Hou WF, Zhang RR, Zhou JJ, Zhang DW
Theranostics 2024;14(13):5001-5021

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MG53 inhibits ferroptosis by targeting the p53/SLC7A11/GPX4 pathway to alleviate doxorubicin-induced cardiotoxicity.

Jiang W, Yu L, Mu N, Zhang Z, Ma H
Free radical biology & medicine 2024 Oct;223:224-236

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Ankrd1 regulates endogenous cardiac regeneration in mice by modulating cyclin D1.

Liu L, Jiang Q, Du C, Yang T, Zhou L, Chen J, Gu L, Wang Q, Wang Z, Wang H, Wang L
European journal of pharmacology 2024 Nov 15;983:177005

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MG53/GMs/HA-Dex neural scaffold promotes the functional recovery of spinal cord injury by alleviating neuroinflammation.

Li X, Ji R, Duan L, Hao Z, Su Y, Wang H, Guan F, Ma S
International journal of biological macromolecules 2024 May;267(Pt 2):131520

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Curculigoside Attenuates Endoplasmic Reticulum Stress-Induced Epithelial Cell and Fibroblast Senescence by Regulating the SIRT1-P300 Signaling Pathway.

Xie W, Deng L, Qian R, Huang X, Liu W, Tang S
Antioxidants (Basel, Switzerland) 2024 Mar 29;13(4)

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MG53 binding to CAV3 facilitates activation of eNOS/NO signaling pathway to enhance the therapeutic benefits of bone marrow-derived mesenchymal stem cells in diabetic wound healing.

Wu J, Feng Y, Wang Y, He X, Chen Z, Lan D, Wu X, Wen J, Tsung A, Wang X, Ma J, Wu Y
International immunopharmacology 2024 Jul 30;136:112410

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LINC01852 inhibits the tumorigenesis and chemoresistance in colorectal cancer by suppressing SRSF5-mediated alternative splicing of PKM.

Bian Z, Yang F, Xu P, Gao G, Yang C, Cao Y, Yao S, Wang X, Yin Y, Fei B, Huang Z
Molecular cancer 2024 Jan 24;23(1):23

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TRIM72 restricts lyssavirus infection by inducing K48-linked ubiquitination and proteasome degradation of the matrix protein.

Sui B, Zheng J, Fu Z, Zhao L, Zhou M
PLoS pathogens 2024 Feb;20(2):e1011718

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PTEN Inhibitor Treatment Lowers Muscle Plasma Membrane Damage and Enhances Muscle ECM Homeostasis after High-Intensity Eccentric Exercise in Mice.

Wu B, Shi L, Wu Y
International journal of molecular sciences 2023 Jun 9;24(12)

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Integrated transcriptomic and proteomic analysis reveals potential targets for heart regeneration.

Liu L, Yang T, Jiang Q, Sun J, Gu L, Wang S, Li Y, Chen B, Zhao D, Sun R, Wang Q, Wang H, Wang L
Biomolecules & biomedicine 2023 Feb 1;23(1):101-113

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Ubiquitination and degradation of MGMT by TRIM72 increases the sensitivity of uveal melanoma cells to Dacarbazine treatment.

Li X, Yang C, Luo N, Yang Y, Guo Y, Chen P, Cun B
Cancer biomarkers : section A of Disease markers 2022;34(2):275-284

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Rosuvastatin exerts cardioprotective effect in lipopolysaccharide-mediated injury of cardiomyocytes in an MG53-dependent manner.

Zhuang J, Cheng G, Huang J, Guo H, Lai Y, Wang J, Shan Z, Zheng S
BMC cardiovascular disorders 2022 Feb 23;22(1):69

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Mesenchymal stem cells-derived exosomes prevent sepsis-induced myocardial injury by a CircRTN4/miR-497-5p/MG53 pathway.

Li J, Jiang R, Hou Y, Lin A
Biochemical and biophysical research communications 2022 Aug 27;618:133-140

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Chorionic villus-derived mesenchymal stem cells induce E3 ligase TRIM72 expression and regulate cell behaviors through ubiquitination of p53 in trophoblasts.

Li Y, Wang C, Xi HM, Li WT, Liu YJ, Feng S, Chu YJ, Wang YH
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Dec;35(12):e22005