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- References [13]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 20341-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- APJ antibody
- Antibody type
- Polyclonal
- Description
- APJ antibody (Cat. #20341-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Apelin/APJ-Manipulated CaMKK/AMPK/GSK3β Signaling Works as an Endogenous Counterinjury Mechanism in Promoting the Vitality of Random-Pattern Skin Flaps.
Hsa_circ_0123190 acts as a competitive endogenous RNA to regulate APLNR expression by sponging hsa-miR-483-3p in lupus nephritis.
Apelin-13 induces mitophagy in bone marrow mesenchymal stem cells to suppress intracellular oxidative stress and ameliorate osteoporosis by activation of AMPK signaling pathway.
Rip 1-dependent endothelial necroptosis participates in ischemia-reperfusion injury of mouse flap.
ELABELA ameliorates hypoxic/ischemic-induced bone mesenchymal stem cell apoptosis via alleviation of mitochondrial dysfunction and activation of PI3K/AKT and ERK1/2 pathways.
Maternal Inactivity Programs Skeletal Muscle Dysfunction in Offspring Mice by Attenuating Apelin Signaling and Mitochondrial Biogenesis.
Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis.
Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer's Disease Through Activation of BDNF-TrkB Signaling Pathway.
APLNR is involved in ATRA-induced growth inhibition of nasopharyngeal carcinoma and may suppress EMT through PI3K-Akt-mTOR signaling.
Molecular determinants of nephron vascular specialization in the kidney.
Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions.
The Hippocampus is a Critical Site Mediating Antidepressant-like Activity of Apelin-13 in Rats.
Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways.
Lou ZL, Zhang CX, Li JF, Chen RH, Wu WJ, Hu XF, Shi HC, Gao WY, Zhao QF
Oxidative medicine and cellular longevity 2021;2021:8836058
Oxidative medicine and cellular longevity 2021;2021:8836058
Hsa_circ_0123190 acts as a competitive endogenous RNA to regulate APLNR expression by sponging hsa-miR-483-3p in lupus nephritis.
Zhang C, Gao C, Di X, Cui S, Liang W, Sun W, Yao M, Liu S, Zheng Z
Arthritis research & therapy 2021 Jan 13;23(1):24
Arthritis research & therapy 2021 Jan 13;23(1):24
Apelin-13 induces mitophagy in bone marrow mesenchymal stem cells to suppress intracellular oxidative stress and ameliorate osteoporosis by activation of AMPK signaling pathway.
Chen L, Shi X, Xie J, Weng SJ, Xie ZJ, Tang JH, Yan DY, Wang BZ, Fang KH, Hong CX, Wu ZY, Yang L
Free radical biology & medicine 2021 Feb 1;163:356-368
Free radical biology & medicine 2021 Feb 1;163:356-368
Rip 1-dependent endothelial necroptosis participates in ischemia-reperfusion injury of mouse flap.
Geng L, Zhang G, Yao M, Fang Y
Journal of dermatological science 2020 Jan;97(1):30-40
Journal of dermatological science 2020 Jan;97(1):30-40
ELABELA ameliorates hypoxic/ischemic-induced bone mesenchymal stem cell apoptosis via alleviation of mitochondrial dysfunction and activation of PI3K/AKT and ERK1/2 pathways.
Fu J, Chen X, Liu X, Xu D, Yang H, Zeng C, Long H, Zhou C, Wu H, Zheng G, Wu H, Wang W, Wang T
Stem cell research & therapy 2020 Dec 14;11(1):541
Stem cell research & therapy 2020 Dec 14;11(1):541
Maternal Inactivity Programs Skeletal Muscle Dysfunction in Offspring Mice by Attenuating Apelin Signaling and Mitochondrial Biogenesis.
Son JS, Chae SA, Wang H, Chen Y, Bravo Iniguez A, de Avila JM, Jiang Z, Zhu MJ, Du M
Cell reports 2020 Dec 1;33(9):108461
Cell reports 2020 Dec 1;33(9):108461
Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis.
Rohlenova K, Goveia J, García-Caballero M, Subramanian A, Kalucka J, Treps L, Falkenberg KD, de Rooij LPMH, Zheng Y, Lin L, Sokol L, Teuwen LA, Geldhof V, Taverna F, Pircher A, Conradi LC, Khan S, Stegen S, Panovska D, De Smet F, Staal FJT, Mclaughlin RJ, Vinckier S, Van Bergen T, Ectors N, De Haes P, Wang J, Bolund L, Schoonjans L, Karakach TK, Yang H, Carmeliet G, Liu Y, Thienpont B, Dewerchin M, Eelen G, Li X, Luo Y, Carmeliet P
Cell metabolism 2020 Apr 7;31(4):862-877.e14
Cell metabolism 2020 Apr 7;31(4):862-877.e14
Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer's Disease Through Activation of BDNF-TrkB Signaling Pathway.
Luo H, Xiang Y, Qu X, Liu H, Liu C, Li G, Han L, Qin X
Frontiers in pharmacology 2019;10:395
Frontiers in pharmacology 2019;10:395
APLNR is involved in ATRA-induced growth inhibition of nasopharyngeal carcinoma and may suppress EMT through PI3K-Akt-mTOR signaling.
Liu Y, Liu Q, Chen S, Liu Y, Huang Y, Chen P, Li X, Gao G, Xu K, Fan S, Zeng Z, Xiong W, Tan M, Li G, Zhang W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):11959-11972
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):11959-11972
Molecular determinants of nephron vascular specialization in the kidney.
Barry DM, McMillan EA, Kunar B, Lis R, Zhang T, Lu T, Daniel E, Yokoyama M, Gomez-Salinero JM, Sureshbabu A, Cleaver O, Di Lorenzo A, Choi ME, Xiang J, Redmond D, Rabbany SY, Muthukumar T, Rafii S
Nature communications 2019 Dec 13;10(1):5705
Nature communications 2019 Dec 13;10(1):5705
Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions.
Dai TT, Wang B, Xiao ZY, You Y, Tian SW
Neuroscience 2018 Oct 15;390:151-159
Neuroscience 2018 Oct 15;390:151-159
The Hippocampus is a Critical Site Mediating Antidepressant-like Activity of Apelin-13 in Rats.
Xiao ZY, Wang B, Fu W, Jin X, You Y, Tian SW, Kuang X
Neuroscience 2018 Apr 1;375:1-9
Neuroscience 2018 Apr 1;375:1-9
Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways.
Yuan ZS, Zhou YZ, Liao XB, Luo JW, Shen KJ, Hu YR, Gu L, Li JM, Tan CM, Chen HM, Zhou XM
Amino acids 2015 Dec;47(12):2475-82
Amino acids 2015 Dec;47(12):2475-82
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 20341-1-AP( APLNR Antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The APLNR antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human APLNR. This antibody recognizes human, mouse antigen. The APLNR antibody has been validated for the following applications: ELISA, WB, IHC analysis.
