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- Antigen structure
- References [22]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 13884-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13884-1-AP, RRID:AB_2188522
- Product name
- NKCC1,SLC12A2 antibody
- Antibody type
- Polyclonal
- Description
- NKCC1,SLC12A2 antibody (Cat. #13884-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Time-dependent effects of tumor necrosis factor α on Ca(2+)-dependent secretion in murine small intestinal organoids.
High correlated color temperature artificial lighting impairs retinal pigment epithelium integrity and chloride ion transport: A potential mechanism for choroidal thinning.
1,2-Dichloroethane causes anxiety and cognitive dysfunction in mice by disturbing GABA metabolism and inhibiting the cAMP-PKA-CREB signaling pathway.
Targeting gut microbial nitrogen recycling and cellular uptake of ammonium to improve bortezomib resistance in multiple myeloma.
Comprehensive analyses of solute carrier family members identify SLC12A2 as a novel therapy target for colorectal cancer.
Unilateral optogenetic kindling of hippocampus leads to more severe impairments of the inhibitory signaling in the contralateral hippocampus.
Alterations in histology of the aging salivary gland and correlation with the glandular inflammatory microenvironment.
Intestinal Cckbr-specific knockout mouse as a novel model of salt-sensitive hypertension via sodium over-absorption.
Correlation of age at seizure onset with GABA(A) receptor subunit and chloride Co-transporter configuration in Focal cortical dysplasia (FCD).
Choroid plexus mast cells drive tumor-associated hydrocephalus.
Atlas of human dental pulp cells at multiple spatial and temporal levels based on single-cell sequencing analysis.
The NKCC1 ion transporter modulates microglial phenotype and inflammatory response to brain injury in a cell-autonomous manner.
Novel γ-sarcoglycan interactors in murine muscle membranes.
NKCC1 promotes proliferation, invasion and migration in human gastric cancer cells via activation of the MAPK-JNK/EMT signaling pathway.
WNK3 Promotes Neuronal Survival after Traumatic Brain Injury in Rats.
Parasympathectomy increases resting secretion of the submandibular gland in minipigs in the long term.
Early uneven ear input induces long-lasting differences in left-right motor function.
Discovery of NKCC1 as a potential therapeutic target to inhibit hepatocellular carcinoma cell growth and metastasis.
The Severity of Vestibular Dysfunction in Deafness as a Determinant of Comorbid Hyperactivity or Anxiety.
Regulation of GABA Equilibrium Potential by mGluRs in Rat Hippocampal CA1 Neurons.
Bile deficiency induces changes in intestinal Cl(-) and HCO3 (-) secretions in mice.
A causative link between inner ear defects and long-term striatal dysfunction.
Pauer SM, Buß B, Diener M, Ballout J
Frontiers in physiology 2024;15:1382238
Frontiers in physiology 2024;15:1382238
High correlated color temperature artificial lighting impairs retinal pigment epithelium integrity and chloride ion transport: A potential mechanism for choroidal thinning.
Zhang C, Jiao Q, Wang M, Zhu Z, Zhao J, Zheng Y
Biochemical and biophysical research communications 2024 Jul 23;718:150078
Biochemical and biophysical research communications 2024 Jul 23;718:150078
1,2-Dichloroethane causes anxiety and cognitive dysfunction in mice by disturbing GABA metabolism and inhibiting the cAMP-PKA-CREB signaling pathway.
Qin Y, Huang W, Wang Z, Wang C, Wang C, Zhang M, Wu S, Wang G, Zhao F
Ecotoxicology and environmental safety 2024 Jul 1;279:116464
Ecotoxicology and environmental safety 2024 Jul 1;279:116464
Targeting gut microbial nitrogen recycling and cellular uptake of ammonium to improve bortezomib resistance in multiple myeloma.
Zhu Y, Jian X, Chen S, An G, Jiang D, Yang Q, Zhang J, Hu J, Qiu Y, Feng X, Guo J, Chen X, Li Z, Zhou R, Hu C, He N, Shi F, Huang S, Liu H, Li X, Xie L, Zhu Y, Zhao L, Jiang Y, Li J, Wang J, Qiu L, Chen X, Jia W, He Y, Zhou W
Cell metabolism 2024 Jan 2;36(1):159-175.e8
Cell metabolism 2024 Jan 2;36(1):159-175.e8
Comprehensive analyses of solute carrier family members identify SLC12A2 as a novel therapy target for colorectal cancer.
Chen DY, Zhang YY, Nie HH, Wang HZ, Qiu PS, Wang F, Peng YN, Xu F, Zhao Q, Zhang M
Scientific reports 2024 Feb 23;14(1):4459
Scientific reports 2024 Feb 23;14(1):4459
Unilateral optogenetic kindling of hippocampus leads to more severe impairments of the inhibitory signaling in the contralateral hippocampus.
Tescarollo FC, Valdivia D, Chen S, Sun H
Frontiers in molecular neuroscience 2023;16:1268311
Frontiers in molecular neuroscience 2023;16:1268311
Alterations in histology of the aging salivary gland and correlation with the glandular inflammatory microenvironment.
Li N, Ye Y, Wu Y, Li L, Hu J, Luo D, Li Y, Yang J, Gao Y, Hai W, Xie Y, Jiang L
iScience 2023 May 19;26(5):106571
iScience 2023 May 19;26(5):106571
Intestinal Cckbr-specific knockout mouse as a novel model of salt-sensitive hypertension via sodium over-absorption.
Zhang QY, Guo Y, Jiang XL, Liu X, Zhao SG, Zhou XL, Yang ZW
Journal of geriatric cardiology : JGC 2023 Jul 28;20(7):538-547
Journal of geriatric cardiology : JGC 2023 Jul 28;20(7):538-547
Correlation of age at seizure onset with GABA(A) receptor subunit and chloride Co-transporter configuration in Focal cortical dysplasia (FCD).
Sharma D, Tripathi M, Doddamani R, Sharma MC, Lalwani S, Sarat Chandra P, Banerjee Dixit A, Banerjee J
Neuroscience letters 2023 Feb 6;796:137065
Neuroscience letters 2023 Feb 6;796:137065
Choroid plexus mast cells drive tumor-associated hydrocephalus.
Li Y, Di C, Song S, Zhang Y, Lu Y, Liao J, Lei B, Zhong J, Guo K, Zhang N, Su S
Cell 2023 Dec 21;186(26):5719-5738.e28
Cell 2023 Dec 21;186(26):5719-5738.e28
Atlas of human dental pulp cells at multiple spatial and temporal levels based on single-cell sequencing analysis.
Ren H, Wen Q, Zhao Q, Wang N, Zhao Y
Frontiers in physiology 2022;13:993478
Frontiers in physiology 2022;13:993478
The NKCC1 ion transporter modulates microglial phenotype and inflammatory response to brain injury in a cell-autonomous manner.
Tóth K, Lénárt N, Berki P, Fekete R, Szabadits E, Pósfai B, Cserép C, Alatshan A, Benkő S, Kiss D, Hübner CA, Gulyás A, Kaila K, Környei Z, Dénes Á
PLoS biology 2022 Jan;20(1):e3001526
PLoS biology 2022 Jan;20(1):e3001526
Novel γ-sarcoglycan interactors in murine muscle membranes.
Smith TC, Vasilakos G, Shaffer SA, Puglise JM, Chou CH, Barton ER, Luna EJ
Skeletal muscle 2022 Jan 22;12(1):2
Skeletal muscle 2022 Jan 22;12(1):2
NKCC1 promotes proliferation, invasion and migration in human gastric cancer cells via activation of the MAPK-JNK/EMT signaling pathway.
Wang JF, Zhao K, Chen YY, Qiu Y, Zhu JH, Li BP, Wang Z, Chen JQ
Journal of Cancer 2021;12(1):253-263
Journal of Cancer 2021;12(1):253-263
WNK3 Promotes Neuronal Survival after Traumatic Brain Injury in Rats.
Zhu J, Lin X, Chen C, Tan H, Gao Y, Li D, Chen G
Neuroscience 2021 Nov 21;477:76-88
Neuroscience 2021 Nov 21;477:76-88
Parasympathectomy increases resting secretion of the submandibular gland in minipigs in the long term.
Zhang XM, Huang Y, Cong X, Qu LH, Zhang K, Wu LL, Zhang Y, Yu GY
Journal of cellular physiology 2019 Jun;234(6):9515-9524
Journal of cellular physiology 2019 Jun;234(6):9515-9524
Early uneven ear input induces long-lasting differences in left-right motor function.
Antoine MW, Zhu X, Dieterich M, Brandt T, Vijayakumar S, McKeehan N, Arezzo JC, Zukin RS, Borkholder DA, Jones SM, Frisina RD, Hébert JM
PLoS biology 2018 Mar;16(3):e2002988
PLoS biology 2018 Mar;16(3):e2002988
Discovery of NKCC1 as a potential therapeutic target to inhibit hepatocellular carcinoma cell growth and metastasis.
Zhou Y, Sun W, Chen N, Xu C, Wang X, Dong K, Zhang B, Zhang J, Hao N, Sun A, Wei H, He F, Jiang Y
Oncotarget 2017 Sep 12;8(39):66328-66342
Oncotarget 2017 Sep 12;8(39):66328-66342
The Severity of Vestibular Dysfunction in Deafness as a Determinant of Comorbid Hyperactivity or Anxiety.
Antoine MW, Vijayakumar S, McKeehan N, Jones SM, Hébert JM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 May 17;37(20):5144-5154
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 May 17;37(20):5144-5154
Regulation of GABA Equilibrium Potential by mGluRs in Rat Hippocampal CA1 Neurons.
Yang B, Rajput PS, Kumar U, Sastry BR
PloS one 2015;10(9):e0138215
PloS one 2015;10(9):e0138215
Bile deficiency induces changes in intestinal Cl(-) and HCO3 (-) secretions in mice.
Song P, Du Y, Song W, Liu X, Hong L, Li H, Xie H, Zhou L, Tuo B, Zheng S
Acta physiologica (Oxford, England) 2014 Jun;211(2):421-33
Acta physiologica (Oxford, England) 2014 Jun;211(2):421-33
A causative link between inner ear defects and long-term striatal dysfunction.
Antoine MW, Hübner CA, Arezzo JC, Hébert JM
Science (New York, N.Y.) 2013 Sep 6;341(6150):1120-3
Science (New York, N.Y.) 2013 Sep 6;341(6150):1120-3
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 13884-1-AP(SLC12A2 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 13884-1-AP(SLC12A2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SLC12A2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SLC12A2. This antibody recognizes human, mouse, rat antigen. The SLC12A2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
