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Protein structure
FOXN1
Forkhead box N1FKHL20, RONU, WHN
Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| antibodies-online |  ABIN1387592 |
1 references | Polyclonal |
WB
ICC
IHC
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| LSBio | LS-C498877 |
Polyclonal |
WB
EL
IHC
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| Bioss | bs-6970R |
2 references | Polyclonal |
WB
ICC
IHC
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| Novus Biologicals | NB100-1302 |
1 references | Polyclonal |
EL
IHC
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| Abbexa | abx026581 |
Polyclonal |
WB
EL
FC
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