DPABH-09592

antibody from Creative Diagnostics

Targeting: PRG2 BMPG, MBP, proMBP

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DPABH-09592

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-09592, RRID:AB_2510998

Product name

Rabbit Anti-Human PRG2 Polyclonal Antibody

Antibody type

Polyclonal

Description

The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 _L

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C. Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.