APR00147G

antibody from Leading Biology

Targeting: HDAC7 DKFZP586J0917, HDAC7A

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APR00147G

Provider

Leading Biology

Product name

HDAC7 Antibody

Antibody type

Polyclonal

Description

Human HDAC7 is composed of 912 amino acid residues. Altho μgh HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, s μggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.