Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 13347-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13347-2-AP, RRID:AB_2142537
- Product name
- MCM6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MCM6 antibody (Cat. #13347-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Systematic analysis of expression and prognostic significance for MCM family in head and neck squamous cell carcinoma.
UBE3A and MCM6 synergistically regulate the proliferation and migration of lung adenocarcinoma cells.
MCM6 is a Poor Prognostic Biomarker and Promotes Progression in Breast Cancer.
Proteogenomic insights into the biology and treatment of pancreatic ductal adenocarcinoma.
Cadherin-16 inhibits thyroid carcinoma cell proliferation and invasion.
Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis.
ACTL6A deficiency induces apoptosis through impairing DNA replication and inhibiting the ATR-Chk1 signaling in glioblastoma cells.
MCMBP promotes the assembly of the MCM2-7 hetero-hexamer to ensure robust DNA replication in human cells.
The influence of phenolic environmental estrogen on the transcriptome of uterine leiomyoma cells: A whole transcriptome profiling-based analysis.
Plasma membrane calcium ATPase 1 regulates human umbilical vein endothelial cell angiogenesis and viability.
METTL3 Promotes the Progression of Gastric Cancer via Targeting the MYC Pathway.
Minichromosome maintenance 6 complex component identified by bioinformatics analysis and experimental validation in esophageal squamous cell carcinoma.
CtIP promotes G2/M arrest in etoposide-treated HCT116 cells in a p53-independent manner.
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
MCM6 promotes metastasis of hepatocellular carcinoma via MEK/ERK pathway and serves as a novel serum biomarker for early recurrence.
Overexpression of MCM6 predicts poor survival in patients with glioma.
MCMs expression in lung cancer: implication of prognostic significance.
RACK1 promotes lung cancer cell growth via an MCM7/RACK1/ Akt signaling complex.
Lamin B2 binding to minichromosome maintenance complex component 7 promotes non-small cell lung carcinogenesis.
Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity.
A panel of protein markers for the early detection of lung cancer with bronchial brushing specimens.
Sun E, Peng L, Liu Z, Yan Z, Chen M, Zheng J
Histology and histopathology 2024 Apr;39(4):471-482
Histology and histopathology 2024 Apr;39(4):471-482
UBE3A and MCM6 synergistically regulate the proliferation and migration of lung adenocarcinoma cells.
Luo Y, Yang Y, Yang C, Li C, Hu R, Geng W, Kang X, Lin H
FEBS open bio 2023 Sep;13(9):1756-1771
FEBS open bio 2023 Sep;13(9):1756-1771
MCM6 is a Poor Prognostic Biomarker and Promotes Progression in Breast Cancer.
Lei Z, Wang P, Jia DQ, Li LL, Wu YP, Yang Y, Pan GQ
Frontiers in bioscience (Landmark edition) 2023 Aug 30;28(8):128
Frontiers in bioscience (Landmark edition) 2023 Aug 30;28(8):128
Proteogenomic insights into the biology and treatment of pancreatic ductal adenocarcinoma.
Tong Y, Sun M, Chen L, Wang Y, Li Y, Li L, Zhang X, Cai Y, Qie J, Pang Y, Xu Z, Zhao J, Zhang X, Liu Y, Tian S, Qin Z, Feng J, Zhang F, Zhu J, Xu Y, Lou W, Ji Y, Zhao J, He F, Hou Y, Ding C
Journal of hematology & oncology 2022 Nov 25;15(1):168
Journal of hematology & oncology 2022 Nov 25;15(1):168
Cadherin-16 inhibits thyroid carcinoma cell proliferation and invasion.
Yang X, Li Y, Liu G, Zha W, Liu Y
Oncology letters 2022 May;23(5):145
Oncology letters 2022 May;23(5):145
Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis.
Shen M, Wei Y, Kim H, Wan L, Jiang YZ, Hang X, Raba M, Remiszewski S, Rowicki M, Wu CG, Wu S, Zhang L, Lu X, Yuan M, Smith HA, Zheng A, Bertino J, Jin JF, Xing Y, Shao ZM, Kang Y
Nature cancer 2022 Jan;3(1):43-59
Nature cancer 2022 Jan;3(1):43-59
ACTL6A deficiency induces apoptosis through impairing DNA replication and inhibiting the ATR-Chk1 signaling in glioblastoma cells.
Hu X, Pei D, Ci M, Zhang G, Li B, Wang J, Shen Y, Zhai X, Liang P, Cui H
Biochemical and biophysical research communications 2022 Apr 9;599:148-155
Biochemical and biophysical research communications 2022 Apr 9;599:148-155
MCMBP promotes the assembly of the MCM2-7 hetero-hexamer to ensure robust DNA replication in human cells.
Saito Y, Santosa V, Ishiguro KI, Kanemaki MT
eLife 2022 Apr 19;11
eLife 2022 Apr 19;11
The influence of phenolic environmental estrogen on the transcriptome of uterine leiomyoma cells: A whole transcriptome profiling-based analysis.
Li Z, Yin H, Shen Y, Ren M, Xu X
Ecotoxicology and environmental safety 2021 Mar 15;211:111945
Ecotoxicology and environmental safety 2021 Mar 15;211:111945
Plasma membrane calcium ATPase 1 regulates human umbilical vein endothelial cell angiogenesis and viability.
Njegic A, Swiderska A, Marris C, Armesilla AL, Cartwright EJ
Journal of molecular and cellular cardiology 2021 Jul;156:79-81
Journal of molecular and cellular cardiology 2021 Jul;156:79-81
METTL3 Promotes the Progression of Gastric Cancer via Targeting the MYC Pathway.
Yang DD, Chen ZH, Yu K, Lu JH, Wu QN, Wang Y, Ju HQ, Xu RH, Liu ZX, Zeng ZL
Frontiers in oncology 2020;10:115
Frontiers in oncology 2020;10:115
Minichromosome maintenance 6 complex component identified by bioinformatics analysis and experimental validation in esophageal squamous cell carcinoma.
Li X, Ren Z, Xiong C, Geng J, Li Y, Liu C, Ren C, Liu H
Oncology reports 2020 Sep;44(3):987-1002
Oncology reports 2020 Sep;44(3):987-1002
CtIP promotes G2/M arrest in etoposide-treated HCT116 cells in a p53-independent manner.
Chen H, Shan J, Chen D, Wang R, Qi W, Wang H, Ke Y, Liu W, Zeng X
Journal of cellular physiology 2019 Jul;234(7):11871-11881
Journal of cellular physiology 2019 Jul;234(7):11871-11881
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
Song H, Guo T, Zhao Z, Wei Y, Luo H, Weng W, Zhang R, Zhong M, Chen C, Su J, Shen W
Biomaterials 2018 Sep;178:23-35
Biomaterials 2018 Sep;178:23-35
MCM6 promotes metastasis of hepatocellular carcinoma via MEK/ERK pathway and serves as a novel serum biomarker for early recurrence.
Liu M, Hu Q, Tu M, Wang X, Yang Z, Yang G, Luo R
Journal of experimental & clinical cancer research : CR 2018 Jan 22;37(1):10
Journal of experimental & clinical cancer research : CR 2018 Jan 22;37(1):10
Overexpression of MCM6 predicts poor survival in patients with glioma.
Cai HQ, Cheng ZJ, Zhang HP, Wang PF, Zhang Y, Hao JJ, Wang MR, Wan JH
Human pathology 2018 Aug;78:182-187
Human pathology 2018 Aug;78:182-187
MCMs expression in lung cancer: implication of prognostic significance.
Liu YZ, Wang BS, Jiang YY, Cao J, Hao JJ, Zhang Y, Xu X, Cai Y, Wang MR
Journal of Cancer 2017;8(18):3641-3647
Journal of Cancer 2017;8(18):3641-3647
RACK1 promotes lung cancer cell growth via an MCM7/RACK1/ Akt signaling complex.
Fei L, Ma Y, Zhang M, Liu X, Luo Y, Wang C, Zhang H, Zhang W, Han Y
Oncotarget 2017 Jun 20;8(25):40501-40513
Oncotarget 2017 Jun 20;8(25):40501-40513
Lamin B2 binding to minichromosome maintenance complex component 7 promotes non-small cell lung carcinogenesis.
Ma Y, Fei L, Zhang M, Zhang W, Liu X, Wang C, Luo Y, Zhang H, Han Y
Oncotarget 2017 Dec 1;8(62):104813-104830
Oncotarget 2017 Dec 1;8(62):104813-104830
Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity.
Yuan Q, Han J, Cong W, Ge Y, Ma D, Dai Z, Li Y, Bi X
International journal of nanomedicine 2014;9:4829-46
International journal of nanomedicine 2014;9:4829-46
A panel of protein markers for the early detection of lung cancer with bronchial brushing specimens.
Liu YZ, Jiang YY, Wang BS, Hao JJ, Shang L, Zhang TT, Cao J, Xu X, Zhan QM, Wang MR
Cancer cytopathology 2014 Nov;122(11):833-41
Cancer cytopathology 2014 Nov;122(11):833-41
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 13347-2-AP(MCM6 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-MCM6 (IP:13347-2-AP, 3ug; Detection:13347-2-AP 1:1000) with HeLa cells lysate 3800ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MCM6 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MCM6. This antibody recognizes human,mouse,rat antigen. The MCM6 antibody has been validated for the following applications: ELISA, WB, IP, IHC analysis.