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- Product number
- ABIN783325 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-PKM2 (AA 36-40) antibody
- Antibody type
- Polyclonal
- Description
- Affinity-chromatography using epitope-specific peptide
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
D-S-P-P-I- Epitope
- AA 36-40
- Vial size
- 50 μL
- Storage
- Store (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.
Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis.
Pyruvate kinase type M2 and its role in tumor growth and spreading.
Christofk HR, Vander Heiden MG, Harris MH, Ramanathan A, Gerszten RE, Wei R, Fleming MD, Schreiber SL, Cantley LC
Nature 2008 Mar 13;452(7184):230-3
Nature 2008 Mar 13;452(7184):230-3
Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis.
Dombrauckas JD, Santarsiero BD, Mesecar AD
Biochemistry 2005 Jul 12;44(27):9417-29
Biochemistry 2005 Jul 12;44(27):9417-29
Pyruvate kinase type M2 and its role in tumor growth and spreading.
Mazurek S, Boschek CB, Hugo F, Eigenbrodt E
Seminars in cancer biology 2005 Aug;15(4):300-8
Seminars in cancer biology 2005 Aug;15(4):300-8
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