Antibody data

Product number
Ab122149 - Provider product page
Provider
Aladdin Scientific
Product name
PKM2 Antibody
Antibody type
Polyclonal
Description
Rabbit anti Human PKM2 Antibody, Polyclonal, could be used for WB, IHC, IF/ICC and so on.Application:WB: 0.01-2µg/mL IHC_5-20µg/mL IF/ICC_5-20µg/mLProtein Function:Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
AA 141~248
Vial size
100_l,10_l,1ml,20_l,50_l
Concentration
Lot by Lot
Storage
Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
PKM protein structure - Ab122149 shown in red.