FNab04517

antibody from FineTest Biotech

Targeting: KEAP1 INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454

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Validation data

Product number: FNab04517 - Provider product page
Provider: FineTest Biotech
Product name: KEAP1 antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
Reactivity: Human, Mouse, Rat
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: kelch-like ECH-associated protein 1
Epitope: IgG2a
Isotype: IgG
Antibody clone number: 900
Vial size: 100¦Ìg
Concentration: Protein A+G purification
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

KEAP1 protein structure - FNab04517 shown in red.