HPA005558

antibody from Atlas Antibodies

Targeting: KEAP1 INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA005558

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA005558, RRID:AB_1079175

Product name

Anti-KEAP1

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human KEAP1, Gene description: kelch-like ECH-associated protein 1, Alternative Gene Names: INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454, Validated applications: IHC, ICC, Uniprot ID: Q14145, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.4 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Downregulation of KEAP1 in melanoma promotes resistance to immune checkpoint blockade

Fox D, Ebright R, Hong X, Russell H, Guo H, LaSalle T, Wittner B, Poux N, Vuille J, Toner M, Hacohen N, Boland G, Sen D, Sullivan R, Maheswaran S, Haber D
npj Precision Oncology 2023;7(1)

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Generation of mitochondrial reactive oxygen species is controlled by ATPase inhibitory factor 1 and regulates cognition

Polleux F, Esparza-Moltó P, Romero-Carramiñana I, Núñez de Arenas C, Pereira M, Blanco N, Pardo B, Bates G, Sánchez-Castillo C, Artuch R, Murphy M, Esteban J, Cuezva J
PLOS Biology 2021;19(5):e3001252

Immunocytochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, cytosol & microtubule organizing center.

Sample type

Human