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- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN500142 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-LAG1 Homolog, Ceramide Synthase 5 (LASS5) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- LASS5 antibody was raised against a 14 amino acid peptide near the amino terminus of the human LASS5.
- Description
- Peptide affinity chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor.
LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia.
Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors.
Coexpression of junctophilin type 3 and type 4 in brain.
Lahiri S, Futerman AH
The Journal of biological chemistry 2005 Oct 7;280(40):33735-8
The Journal of biological chemistry 2005 Oct 7;280(40):33735-8
LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia.
Xu Z, Zhou J, McCoy DM, Mallampalli RK
Journal of lipid research 2005 Jun;46(6):1229-38
Journal of lipid research 2005 Jun;46(6):1229-38
Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors.
Riebeling C, Allegood JC, Wang E, Merrill AH Jr, Futerman AH
The Journal of biological chemistry 2003 Oct 31;278(44):43452-9
The Journal of biological chemistry 2003 Oct 31;278(44):43452-9
Coexpression of junctophilin type 3 and type 4 in brain.
Nishi M, Sakagami H, Komazaki S, Kondo H, Takeshima H
Brain research. Molecular brain research 2003 Oct 21;118(1-2):102-10
Brain research. Molecular brain research 2003 Oct 21;118(1-2):102-10
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of LASS5 in SK-N-SH lysate with AP30492PU-N at (A) 1 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of LASS5 in mouse brain tissue with AP30492PU-N at 2.5 ?g/ml.
