Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [3]
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Validation data
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- Product number
- NB300-124 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB300-124, RRID:AB_2113758
- Product name
- Rabbit Polyclonal mGluR2/3 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specific for the ~110k monomer and the ~220k dimer of mGluR2 and mGluR3. Immunolabeling is blocked by preadsorption of antibody with the peptide used as antigen to generate the antibody.
- Reactivity
- Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology.
5-HT2A-mGlu2/3 receptor complex in rat spinal cord glutamatergic nerve endings: A 5-HT2A to mGlu2/3 signalling to amplify presynaptic mechanism of auto-control of glutamate exocytosis.
Heterogeneity of glycinergic and gabaergic interneurons in the granule cell layer of mouse cerebellum.
Malik AR, Szydlowska K, Nizinska K, Asaro A, van Vliet EA, Popp O, Dittmar G, Fritsche-Guenther R, Kirwan JA, Nykjaer A, Lukasiuk K, Aronica E, Willnow TE
Cell reports 2019 Mar 5;26(10):2792-2804.e6
Cell reports 2019 Mar 5;26(10):2792-2804.e6
5-HT2A-mGlu2/3 receptor complex in rat spinal cord glutamatergic nerve endings: A 5-HT2A to mGlu2/3 signalling to amplify presynaptic mechanism of auto-control of glutamate exocytosis.
Olivero G, Grilli M, Vergassola M, Bonfiglio T, Padolecchia C, Garrone B, Di Giorgio FP, Tongiani S, Usai C, Marchi M, Pittaluga A
Neuropharmacology 2018 May 1;133:429-439
Neuropharmacology 2018 May 1;133:429-439
Heterogeneity of glycinergic and gabaergic interneurons in the granule cell layer of mouse cerebellum.
Simat M, Parpan F, Fritschy JM
The Journal of comparative neurology 2007 Jan 1;500(1):71-83
The Journal of comparative neurology 2007 Jan 1;500(1):71-83
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: metabotropic Glutamate Receptor 2/3 Antibody [NB300-124] - Western blot of 10 ug of HEK 293 cells expression. As shown in the autoradiograph, the mGluR2/3 antibody recognizes both the ~110k monomer and the ~220k dimer of mGluR2 (Lane A) and mGluR3 (Lane B). Also shown is the specific immunolabeling of the monomer
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: metabotropic Glutamate Receptor 2/3 Antibody [NB300-124] - Western blot of 10 ug of rat hippocampal lysate showing the specific immunolabeling of the ~110k monomer and the ~220k dimer of mGluR2 and mGluR3.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: metabotropic Glutamate Receptor 2/3 Antibody [NB300-124] - Specificity of mGluR2/3 (NB 300-124) in rat tissue lysate.