Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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Validation data
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- Product number
- 12564-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12564-1-AP, RRID:AB_2082457
- Product name
- CNOT4 antibody
- Antibody type
- Polyclonal
- Description
- CNOT4 antibody (Cat. #12564-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Stalled translation by mitochondrial stress upregulates a CNOT4-ZNF598 ribosomal quality control pathway important for tissue homeostasis.
Coupled protein quality control during nonsense-mediated mRNA decay.
Disruption of the Mammalian Ccr4-Not Complex Contributes to Transcription-Mediated Genome Instability.
Geng J, Li S, Li Y, Wu Z, Bhurtel S, Rimal S, Khan D, Ohja R, Brandman O, Lu B
Nature communications 2024 Feb 22;15(1):1637
Nature communications 2024 Feb 22;15(1):1637
Coupled protein quality control during nonsense-mediated mRNA decay.
Inglis AJ, Guna A, Gálvez-Merchán Á, Pal A, Esantsi TK, Keys HR, Frenkel EM, Oania R, Weissman JS, Voorhees RM
Journal of cell science 2023 May 15;136(10)
Journal of cell science 2023 May 15;136(10)
Disruption of the Mammalian Ccr4-Not Complex Contributes to Transcription-Mediated Genome Instability.
Hagkarim NC, Hajkarim MC, Suzuki T, Fujiwara T, Winkler GS, Stewart GS, Grand RJ
Cells 2023 Jul 17;12(14)
Cells 2023 Jul 17;12(14)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 12564-1-AP(CNOT4 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using CNOT4 antibody 12564-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 12564-1-AP(CNOT4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CNOT4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CNOT4. This antibody recognizes human,mouse,rat antigen. The CNOT4 antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.