BS7332

antibody from Bioworld Technology, Inc
Targeting: UBE2D1 E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A
Provider product page for BS7332
Western blot
Immunohistochemistry

Antibody data

Product number
BS7332 - Provider product page
Provider
Bioworld Technology, Inc
Product name
UBE2D1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human UBE2D1.
Description
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
UBE2D1 protein structure - BS7332 shown in red.