CABT-BL900

antibody from Creative Diagnostics

Targeting: CCNT2

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

CABT-BL900

Provider

Creative Diagnostics

Product name

Anti-CCNT2 monoclonal antibody, clone 2I4

Antibody type

Monoclonal

Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2I4

Storage

Store at -2°C or lower. Aliquot to avoid repeated freezing and thawing.