Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 23996-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- TFAM antibody
- Antibody type
- Polyclonal
- Description
- TFAM antibody (Cat. #23996-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A tumor-derived mitochondrial tsRNA drives vascular invasion of lung adenocarcinoma by promoting ribosomal assembly in endothelial cells.
Nitric oxide-primed engineered extracellular vesicles restore bioenergetics in acute kidney injury via mitochondrial transfer.
Dental pulp stem cells alleviate Schwann cell pyroptosis via mitochondrial transfer to enhance facial nerve regeneration.
Mitochondria-localized MBD2c facilitates mtDNA transcription and drug resistance.
Mapping the nanoscale organization of the human cell surface proteome reveals new functional associations and surface antigen clusters.
Targeting ATM enhances radiation sensitivity of colorectal cancer by potentiating radiation-induced cell death and antitumor immunity.
Melatonin attenuates intervertebral disc degeneration by restoring mitochondrial homeostasis through PGC-1α signaling pathway.
Lipid droplet formation induced by icaritin derivative IC2 promotes a combination strategy for cancer therapy.
BET inhibition induces GDH1-dependent glutamine metabolic remodeling and vulnerability in liver cancer.
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
Inactivity of Peptidase ClpP Causes Primary Accumulation of Mitochondrial Disaggregase ClpX with Its Interacting Nucleoid Proteins, and of mtDNA.
Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner.
Icariin protects human nucleus pulposus cells from hydrogen peroxide-induced mitochondria-mediated apoptosis by activating nuclear factor erythroid 2-related factor 2.
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
Liang S, Wang Q, Zhang M, Song X, Zhang Y, Wang H, Feng Y, Li R, Xia W, Xu L, Dong G, Mao Q, Jiang F
Cancer letters 2026 Apr 28;644:218324
Cancer letters 2026 Apr 28;644:218324
Nitric oxide-primed engineered extracellular vesicles restore bioenergetics in acute kidney injury via mitochondrial transfer.
Peng F, Chen X, Wu L, He J, Li Z, Hong Q, Zhao Q, Qian M, Wang X, Shen W, Qi T, Huang Y, Cai G, Zhang C, Chen X
Theranostics 2025;15(11):5499-5517
Theranostics 2025;15(11):5499-5517
Dental pulp stem cells alleviate Schwann cell pyroptosis via mitochondrial transfer to enhance facial nerve regeneration.
Zheng X, Wang J, Zhou H, Chai Y, Li Z, Chen M, Yang Z, Xu C, Lei C, He Y, Zou D, Ye Q
Bioactive materials 2025 May;47:313-326
Bioactive materials 2025 May;47:313-326
Mitochondria-localized MBD2c facilitates mtDNA transcription and drug resistance.
Hao Y, Zhou Z, Liu R, Shen S, Liu H, Zhou Y, Sun Y, Mao Q, Zhang T, Li ST, Liu Z, Chu Y, Sun L, Gao P, Zhang H
Nature chemical biology 2025 Jun;21(6):926-938
Nature chemical biology 2025 Jun;21(6):926-938
Mapping the nanoscale organization of the human cell surface proteome reveals new functional associations and surface antigen clusters.
Floyd BM, Schmidt EL, Till NA, Yang JL, Liao P, George BM, Flynn RA, Bertozzi CR
bioRxiv : the preprint server for biology 2025 Feb 17;
bioRxiv : the preprint server for biology 2025 Feb 17;
Targeting ATM enhances radiation sensitivity of colorectal cancer by potentiating radiation-induced cell death and antitumor immunity.
Xie Y, Liu Y, Lin M, Li Z, Shen Z, Yin S, Zheng Y, Zou Y, Zhang Y, Zhan Y, Fang Y, Ding Y
Journal of advanced research 2025 Aug;74:513-530
Journal of advanced research 2025 Aug;74:513-530
Melatonin attenuates intervertebral disc degeneration by restoring mitochondrial homeostasis through PGC-1α signaling pathway.
Lan T, Yang W, Yan B, Guo W, Zhang Y
Cellular and molecular life sciences : CMLS 2025 Aug 31;82(1):330
Cellular and molecular life sciences : CMLS 2025 Aug 31;82(1):330
Lipid droplet formation induced by icaritin derivative IC2 promotes a combination strategy for cancer therapy.
Wu G, Ying L, Zhang Q, Xiong H, Wang J, Chen S, Yang C, Jin Y, Lai Z, Feng N, Ge Y
Chinese medicine 2024 Dec 26;19(1):178
Chinese medicine 2024 Dec 26;19(1):178
BET inhibition induces GDH1-dependent glutamine metabolic remodeling and vulnerability in liver cancer.
Mi W, You J, Li L, Zhu L, Xia X, Yang L, Li F, Xu Y, Bi J, Liu P, Chen L, Li F
Life metabolism 2024 Aug;3(4):loae016
Life metabolism 2024 Aug;3(4):loae016
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
Shu Y, Hao Y, Feng J, Liu H, Li ST, Feng J, Jiang Z, Ye L, Zhou Y, Sun Y, Zhou Z, Wei H, Gao P, Zhang H, Sun L
The EMBO journal 2022 Dec 1;41(23):e111550
The EMBO journal 2022 Dec 1;41(23):e111550
Inactivity of Peptidase ClpP Causes Primary Accumulation of Mitochondrial Disaggregase ClpX with Its Interacting Nucleoid Proteins, and of mtDNA.
Key J, Torres-Odio S, Bach NC, Gispert S, Koepf G, Reichlmeir M, West AP, Prokisch H, Freisinger P, Newman WG, Shalev S, Sieber SA, Wittig I, Auburger G
Cells 2021 Nov 29;10(12)
Cells 2021 Nov 29;10(12)
Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner.
Zhang C, Nie P, Zhou C, Hu Y, Duan S, Gu M, Jiang D, Wang Y, Deng Z, Chen J, Chen S, Wang L
Cell death & disease 2021 Feb 24;12(2):209
Cell death & disease 2021 Feb 24;12(2):209
Icariin protects human nucleus pulposus cells from hydrogen peroxide-induced mitochondria-mediated apoptosis by activating nuclear factor erythroid 2-related factor 2.
Hua W, Li S, Luo R, Wu X, Zhang Y, Liao Z, Song Y, Wang K, Zhao K, Yang S, Yang C
Biochimica et biophysica acta. Molecular basis of disease 2020 Jan 1;1866(1):165575
Biochimica et biophysica acta. Molecular basis of disease 2020 Jan 1;1866(1):165575
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
Aulas A, Lyons SM, Fay MM, Anderson P, Ivanov P
Cell death & disease 2018 Nov 13;9(11):1129
Cell death & disease 2018 Nov 13;9(11):1129
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 23996-1-AP(TFAM antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The TFAM antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TFAM. This antibody recognizes human antigen. The TFAM antibody has been validated for the following applications: ELISA, WB, IHC analysis.