ABIN457963
antibody from antibodies-online
Targeting: SERPING1
C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN457963 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN457963, RRID:AB_10780012
- Product name
- anti-Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1) antibody
- Antibody type
- Polyclonal
- Antigen
- C1 esterase inhibitor is a single chain acid glycoprotein with a molecular weight of 110,000. The protein has a high carbohydrate content. In immunoelectrophoresis it ha an alpha mobility. The concentration in normal serum ranges from 150 to 350 μ g/ml. Reduced levels are observed in hereditary angioedema. It regulates the activation of complement factor C1 as well as the activity of activated C1 by coupling with the active catalytic site at the light chains of C1r and C1s. Moreover it also inhibits, kallikrein, Factor XI and Factor XII. Freund?s complete adjuvant is used in the first step of the immunization procedure.
- Description
- Adsorption: Immunoaffinity adsorbed using insolubilized antigens as required, to eliminate antibodies reacting with other plasma proteins. The use of insolubilized adsorption antigens prevents the presence of excess adsorbent protein or immune complexes in the antiserum.
- Reactivity
- Human
- Host
- Goat
- Isotype
- IgG
- Vial size
- 1 mL
- Concentration
- Total protein and IgG concentrations in the antiserum are comparable to those of pooled normal goat serum. No foreign proteins added. Antibody titre: Precipitin titre 1:32 when tested against pooled normal human plasma in agar-block immunodiffusion titrat
- Storage
- 4°C
No comments: Submit comment
No validations: Submit validation data