AP31526SU-N

antibody from Acris Antibodies GmbH

Targeting: SERPING1 C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

AP31526SU-N

Provider

Acris Antibodies GmbH

Proper citation

Acris Antibodies GmbH Cat#AP31526SU-N, RRID:AB_10977618

Product name

anti SERPING1 / C1 Inhibitor

Antibody type

Polyclonal

Antigen

C1 esterase inhibitor is a single chain acid glycoprotein with a molecular weight of 110,000. The protein has a high carbohydrate content. In immunoelectrophoresis it ha an alpha mobility. The concentration in normal serum ranges from 150 to 350 μg/ml. Reduced levels are observed in hereditary angioedema. It regulates the activation of complement factor C1 as well as the activity of activated C1 by coupling with the active catalytic site at the light chains of C1r and C1s. Moreover it also inhibits, kallikrein, Factor XI and Factor XII. Freund’s complete adjuvant is used in the first step of the immunization procedure.

Reactivity

Human

Host

Rabbit

Vial size

1 ml