Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 17987-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17987-1-AP, RRID:AB_2222383
- Product name
- ADNP antibody
- Antibody type
- Polyclonal
- Description
- ADNP antibody (Cat. #17987-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ADNP missense variant p.C687R disrupts chromatin regulation and GABAergic differentiation in Helsmoortel-Van der Aa syndrome.
Neuron-targeted caveolin-1 overexpression attenuates cognitive loss and pathological transcriptome changes in symptomatic Alzheimer's disease models.
Proteomics reveals the key transcription-related factors mediating obstructive nephropathy in pediatric patients and mice.
A guide to selecting high-performing antibodies for ADNP (UniProt ID: Q9H2P0) for use in western blot, immunoprecipitation, and immunofluorescence.
Clinical impact and in vitro characterization of ADNP variants in pediatric patients.
ADNP prompts the cisplatin-resistance of bladder cancer via TGF-β-mediated epithelial-mesenchymal transition (EMT) pathway.
ADNP Upregulation Promotes Bladder Cancer Cell Proliferation via the AKT Pathway.
Chen Q, Liu X, Wu M, Sun D, Ding X, Zhou M, Peng W, Cheng Y, Xue B, Tang N, Xu G, Tai Y, Xu Q, Xiong M, Jiang Y
Molecular autism 2026 Apr 6;17(1)
Molecular autism 2026 Apr 6;17(1)
Neuron-targeted caveolin-1 overexpression attenuates cognitive loss and pathological transcriptome changes in symptomatic Alzheimer's disease models.
Wang D, Chernov AV, Lam R, Wang H, Li W, Li X, Duong T, Wang S, Head BP
Signal transduction and targeted therapy 2025 May 28;10(1):172
Signal transduction and targeted therapy 2025 May 28;10(1):172
Proteomics reveals the key transcription-related factors mediating obstructive nephropathy in pediatric patients and mice.
Cao H, Tao Y, Jin R, Li P, Zhou H, Cheng J
Renal failure 2025 Dec;47(1):2443032
Renal failure 2025 Dec;47(1):2443032
A guide to selecting high-performing antibodies for ADNP (UniProt ID: Q9H2P0) for use in western blot, immunoprecipitation, and immunofluorescence.
Ruíz Moleón V, Alende C, Fotouhi M, Ayoubi R, González Bolívar S, Laflamme C, NeuroSGC/YCharOS/EDDU collaborative group, ABIF consortium
F1000Research 2024;13:1545
F1000Research 2024;13:1545
Clinical impact and in vitro characterization of ADNP variants in pediatric patients.
Ge C, Tian Y, Hu C, Mei L, Li D, Dong P, Zhang Y, Li H, Sun D, Peng W, Xu X, Jiang Y, Xu Q
Molecular autism 2024 Jan 22;15(1):5
Molecular autism 2024 Jan 22;15(1):5
ADNP prompts the cisplatin-resistance of bladder cancer via TGF-β-mediated epithelial-mesenchymal transition (EMT) pathway.
Xie Y, Zhu S, Zang J, Wu G, Wen Y, Liang Y, Long Y, Guo W, Zang C, Hu X, Fan G, Xiang S, Zhang J
Journal of Cancer 2021;12(17):5114-5124
Journal of Cancer 2021;12(17):5114-5124
ADNP Upregulation Promotes Bladder Cancer Cell Proliferation via the AKT Pathway.
Zhu S, Xu Z, Zeng Y, Long Y, Fan G, Ding Q, Wen Y, Cao J, Dai T, Han W, Xie Y
Frontiers in oncology 2020;10:491129
Frontiers in oncology 2020;10:491129
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 17987-1-AP(ADNP antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunofluorescent analysis of Hela cells, using ADNP antibody 17987-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line