FNab09586

antibody from FineTest Biotech

Targeting: ZBP1 C20orf183, DAI, dJ718J7.3, DLM-1, DLM1

Western blot

ELISA

Immunohistochemistry

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Validation data

Product number: FNab09586 - Provider product page
Provider: FineTest Biotech
Product name: ZBP1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor(IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3(By similarity).
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: Z-DNA binding protein 1
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ZBP1 protein structure - FNab09586 shown in red.