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- References [8]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12597-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12597-1-AP, RRID:AB_10951115
- Product name
- GABPB1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GABPB1 antibody (Cat. #12597-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer.
Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas.
TERT Promoter Revertant Mutation Inhibits Melanoma Growth through Intrinsic Apoptosis.
ZFP36 protects against oxygen-glucose deprivation/reoxygenation-induced mitochondrial fragmentation and neuronal apoptosis through inhibiting NOX4-DRP1 pathway.
Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage.
LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells.
Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner.
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
McKinney AM, Mathur R, Stevers NO, Molinaro AM, Chang SM, Phillips JJ, Costello JF
Cell reports 2022 Sep 20;40(12):111344
Cell reports 2022 Sep 20;40(12):111344
Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas.
Shi Z, Ge X, Li M, Yin J, Wang X, Zhang J, Chen D, Li X, Wang X, Ji J, You Y, Qian X
Molecular cell 2022 Oct 20;82(20):3919-3931.e7
Molecular cell 2022 Oct 20;82(20):3919-3931.e7
TERT Promoter Revertant Mutation Inhibits Melanoma Growth through Intrinsic Apoptosis.
Wang Y, Chen Y, Li C, Xiao Z, Yuan H, Zhang Y, Pang D, Tang X, Li M, Ouyang H
Biology 2022 Jan 14;11(1)
Biology 2022 Jan 14;11(1)
ZFP36 protects against oxygen-glucose deprivation/reoxygenation-induced mitochondrial fragmentation and neuronal apoptosis through inhibiting NOX4-DRP1 pathway.
Guo H, Jiang Y, Gu Z, Ren L, Zhu C, Yu S, Wei R
Brain research bulletin 2022 Feb;179:57-67
Brain research bulletin 2022 Feb;179:57-67
Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage.
Amen AM, Fellmann C, Soczek KM, Ren SM, Lew RJ, Knott GJ, Park JE, McKinney AM, Mancini A, Doudna JA, Costello JF
Proceedings of the National Academy of Sciences of the United States of America 2021 Mar 30;118(13)
Proceedings of the National Academy of Sciences of the United States of America 2021 Mar 30;118(13)
LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells.
Qi W, Li Z, Xia L, Dai J, Zhang Q, Wu C, Xu S
Scientific reports 2019 Nov 7;9(1):16185
Scientific reports 2019 Nov 7;9(1):16185
Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner.
Mancini A, Xavier-Magalhães A, Woods WS, Nguyen KT, Amen AM, Hayes JL, Fellmann C, Gapinske M, McKinney AM, Hong C, Jones LE, Walsh KM, Bell RJA, Doudna JA, Costa BM, Song JS, Perez-Pinera P, Costello JF
Cancer cell 2018 Sep 10;34(3):513-528.e8
Cancer cell 2018 Sep 10;34(3):513-528.e8
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
Wu H, Xiao Y, Zhang S, Ji S, Wei L, Fan F, Geng J, Tian J, Sun X, Qin F, Jin C, Lin J, Yin ZY, Zhang T, Luo L, Li Y, Song S, Lin SC, Deng X, Camargo F, Avruch J, Chen L, Zhou D
Cell reports 2013 May 30;3(5):1663-77
Cell reports 2013 May 30;3(5):1663-77
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 12597-1-AP(GABPB1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GABPB1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GABPB1. This antibody recognizes human,mouse,rat antigen. The GABPB1 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
