ABIN1002685

antibody from antibodies-online

Targeting: NLRC4 CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, ipaf

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN1002685

Provider

antibodies-online

Product name

anti-NLR Family, CARD Domain Containing 4 (NLRC4) antibody

Antibody type

Polyclonal

Antigen

Rabbit polyclol Ipaf antibody was raised against a synthetic peptide corresponding to amino acids near the C-terminus of human Ipaf (Genbank accession NP_067032).

Description

Affinity chromatography purified via peptide column.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100 μg

Storage

4°C

Handling

Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.

References

Submitted references

Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis.

Geddes BJ, Wang L, Huang WJ, Lavellee M, Manji GA, Brown M, Jurman M, Cao J, Morgenstern J, Merriam S, Glucksmann MA, DiStefano PS, Bertin J
Biochemical and biophysical research communications 2001 Jun 1;284(1):77-82

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Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1.

Poyet JL, Srinivasula SM, Tnani M, Razmara M, Fernandes-Alnemri T, Alnemri ES
The Journal of biological chemistry 2001 Jul 27;276(30):28309-13

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.

Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X
Cell 1997 Nov 14;91(4):479-89