Explore
Validate
Learn15449-1-AP
antibody from Proteintech Group
Targeting: NSUN5
FLJ10267, NOL1R, NSUN5A, p120(NOL1), WBSCR20, WBSCR20A, Ynl022cL
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 15449-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15449-1-AP, RRID:AB_2153808
- Product name
- NSUN5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NSUN5 antibody (Cat. #15449-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Niujiao Dihuang Jiedu decoction promotes SLC7A11 m5C methylation modification against ferroptosis in acute-on-chronic liver failure.
NSUN5-FTH1 Axis Inhibits Ferroptosis to Promote the Growth of Gastric Cancer Cells.
Epitranscriptomic subtyping, visualization, and denoising by global motif visualization.
m(5)C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization.
The NSUN5-FTH1/FTL pathway mediates ferroptosis in bone marrow-derived mesenchymal stem cells.
NSUN5 promotes progression and predicts poor prognosis in hepatocellular carcinoma.
Identification of Expression Patterns and Potential Prognostic Significance of m(5)C-Related Regulators in Head and Neck Squamous Cell Carcinoma.
Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated dihydrouridylation.
Agenesis and Hypomyelination of Corpus Callosum in Mice Lacking Nsun5, an RNA Methyltransferase.
Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex.
Cognitive deficits in mice lacking Nsun5, a cytosine-5 RNA methyltransferase, with impairment of oligodendrocyte precursor cells.
Huang L, Liu J, Jin Y, Qiu Y, Qin X, Wu S, Chen D, Bie C, Kuang W, Liu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155136
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155136
NSUN5-FTH1 Axis Inhibits Ferroptosis to Promote the Growth of Gastric Cancer Cells.
Su Y, Liu J, Zheng Z, Shi L, Huang W, Huang X, Ye C, Qi J, Wang W, Zhuang H
Cell biochemistry and biophysics 2023 Sep;81(3):553-560
Cell biochemistry and biophysics 2023 Sep;81(3):553-560
Epitranscriptomic subtyping, visualization, and denoising by global motif visualization.
Liu J, Huang T, Yao J, Zhao T, Zhang Y, Zhang R
Nature communications 2023 Sep 23;14(1):5944
Nature communications 2023 Sep 23;14(1):5944
m(5)C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization.
Wang N, Chen RX, Deng MH, Wei WS, Zhou ZH, Ning K, Li YH, Li XD, Ye YL, Wen JH, Dong B, Zhang XP, Liu ZW, Zhou FJ
Cell death & disease 2023 Feb 18;14(2):139
Cell death & disease 2023 Feb 18;14(2):139
The NSUN5-FTH1/FTL pathway mediates ferroptosis in bone marrow-derived mesenchymal stem cells.
Liu J, Ren Z, Yang L, Zhu L, Li Y, Bie C, Liu H, Ji Y, Chen D, Zhu M, Kuang W
Cell death discovery 2022 Mar 5;8(1):99
Cell death discovery 2022 Mar 5;8(1):99
NSUN5 promotes progression and predicts poor prognosis in hepatocellular carcinoma.
Zhang XW, Wu LY, Liu HR, Huang Y, Qi Q, Zhong R, Zhu L, Gao CF, Zhou L, Yu J, Wu HG
Oncology letters 2022 Dec;24(6):439
Oncology letters 2022 Dec;24(6):439
Identification of Expression Patterns and Potential Prognostic Significance of m(5)C-Related Regulators in Head and Neck Squamous Cell Carcinoma.
Han Z, Yang B, Wang Y, Zeng X, Tian Z
Frontiers in oncology 2021;11:592107
Frontiers in oncology 2021;11:592107
Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated dihydrouridylation.
Dai W, Li A, Yu NJ, Nguyen T, Leach RW, Wühr M, Kleiner RE
Nature chemical biology 2021 Nov;17(11):1178-1187
Nature chemical biology 2021 Nov;17(11):1178-1187
Agenesis and Hypomyelination of Corpus Callosum in Mice Lacking Nsun5, an RNA Methyltransferase.
Yuan Z, Chen P, Zhang T, Shen B, Chen L
Cells 2019 Jun 6;8(6)
Cells 2019 Jun 6;8(6)
Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex.
Chen P, Zhang T, Yuan Z, Shen B, Chen L
Molecular brain 2019 Aug 28;12(1):74
Molecular brain 2019 Aug 28;12(1):74
Cognitive deficits in mice lacking Nsun5, a cytosine-5 RNA methyltransferase, with impairment of oligodendrocyte precursor cells.
Zhang T, Chen P, Li W, Sha S, Wang Y, Yuan Z, Shen B, Chen L
Glia 2019 Apr;67(4):688-702
Glia 2019 Apr;67(4):688-702
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human placenta tissue were subjected to SDS PAGE followed by western blot with 15449-1-AP(NSUN5 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using NSUN5 antibody 15449-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin cancer using 15449-1-AP(NSUN5 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin cancer using 15449-1-AP(NSUN5 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
