Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11-4021 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-NR2F6 Antibody
- Antibody type
- Polyclonal
- Description
- NR2F6 (Nuclear receptor subfamily 2 group F member 6) is a nuclear zinc-finger orphan receptor which acts as a critical PKC (protein kinase C) substrate and essential regulator of CD4(+) T cell activation responses. It Inhibits NFATC (Nuclear factor of activated T-cells) transcription factor DNA binding and subsequently its transcriptional activity. It acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4+ T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. It is involved in development of forebrain circadian clock.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant NR2F6
protein (amino acids 210-400) was u
sed as the immunogen for this antib
ody.- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of NR2F6. Anti-NR2F6 antibody (11-4021) was used at 4 µg/ml on MCF-7 lysate.
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of NR2F6. Anti-NR2F6 antibody (11-4021) in human Testis tissue at 5 µg/ml.