PA5-36164

antibody from Invitrogen Antibodies

Targeting: HOXA1 HOX1, HOX1F

Western blot (Data presented on provider website)

Other assay (Supportive data in Antibodypedia)

Antibody Data

Product number

PA5-36164

Provider

Invitrogen Antibodies

Product name

HOXA1 Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

This antibody detects endogenous protein at a molecular weight of 37 kDa. Purity is >95% by SDS-PAGE.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100 µL

Concentration

1 mg/mL

Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

References

Submitted references

Identification of HOXA1 as a Novel Biomarker in Prognosis of Head and Neck Squamous Cell Carcinoma.

Li H, Wang X, Zhang M, Wang M, Zhang J, Ma S
Frontiers in molecular biosciences 2020;7:602068

Other assay

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Figure 3 Transcriptional expression and protein level of HOXA1 is significantly high in HNSCC patients. (A) Higher HOXA1 mRNA expression in 499 tumor tissues compared with 43 para-carcinoma tissues based on TCGA-HNSC DATA ( p = 1.241e-10). (B) Paired difference analysis of HOXA1 mRNA expression based on TCGA-HNSC DATA ( p = 9.984e-09). (C) The percentage of HOXA1-positive area was significantly higher in HNSCC sections than in para-carcinoma sections ( P < 0.0001). (D) The percentage of HOXA1-positive cells was significantly higher in HNSCC sections than in para-carcinoma sections ( P < 0.0001). (E-G) Representative immunohistochemical staining for HOXA1 protein in 52 matched HNSCC tissues and para-carcinoma tissues. (E) Negative expression of HOXA1 in para-carcinoma tissues (-). (F) Low expression of HOXA1 protein in HNSCC specimens (- to +). (G) High expression of HOXA1 protein in primary HNSCC specimens (++). Original magnification: x200 (top), x400 (bottom).