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- Antigen structure
- References [8]
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- Validations
- Western blot [1]
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- Product number
- 20852-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20852-1-AP, RRID:AB_10863659
- Product name
- EZH1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EZH1 antibody (Cat. #20852-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inhibition of protein kinase C increases Prdm14 level to promote self-renewal of embryonic stem cells through reducing Suv39h-induced H3K9 methylation.
Cell surface CD55 traffics to the nucleus leading to cisplatin resistance and stemness by inducing PRC2 and H3K27 trimethylation on chromatin in ovarian cancer.
The m(6)A reader YTHDC2 regulates UVB-induced DNA damage repair and histone modification.
Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling.
Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders.
Discovery of precision targeting EZH2 degraders for triple-negative breast cancer.
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Ezh1 regulates expression of Cpg15/Neuritin in mouse cortical neurons.
Ji J, Cao J, Chen P, Huang R, Ye SD
The Journal of biological chemistry 2024 Mar;300(3):105714
The Journal of biological chemistry 2024 Mar;300(3):105714
Cell surface CD55 traffics to the nucleus leading to cisplatin resistance and stemness by inducing PRC2 and H3K27 trimethylation on chromatin in ovarian cancer.
Bharti R, Dey G, Khan D, Myers A, Huffman OG, Saygin C, Braley C, Richards E, Sangwan N, Willard B, Lathia JD, Fox PL, Lin F, Jha BK, Brown JM, Yu JS, Dwidar M, Joehlin-Price A, Vargas R, Michener CM, Longworth MS, Reizes O
Molecular cancer 2024 Jun 10;23(1):121
Molecular cancer 2024 Jun 10;23(1):121
The m(6)A reader YTHDC2 regulates UVB-induced DNA damage repair and histone modification.
Yang Z, Verghese M, Yang S, Shah P, He YY
Photochemistry and photobiology 2024 Jul-Aug;100(4):1031-1040
Photochemistry and photobiology 2024 Jul-Aug;100(4):1031-1040
Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling.
Feng X, Wang AH, Juan AH, Ko KD, Jiang K, Riparini G, Ciuffoli V, Kaba A, Lopez C, Naz F, Jarnik M, Aliberti E, Hu S, Segalés J, Khateb M, Acevedo-Luna N, Randazzo D, Cheung TH, Muñoz-Cánoves P, Dell'Orso S, Sartorelli V
Developmental cell 2023 Jun 19;58(12):1052-1070.e10
Developmental cell 2023 Jun 19;58(12):1052-1070.e10
Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders.
Gracia-Diaz C, Zhou Y, Yang Q, Maroofian R, Espana-Bonilla P, Lee CH, Zhang S, Padilla N, Fueyo R, Waxman EA, Lei S, Otrimski G, Li D, Sheppard SE, Mark P, Harr MH, Hakonarson H, Rodan L, Jackson A, Vasudevan P, Powel C, Mohammed S, Maddirevula S, Alzaidan H, Faqeih EA, Efthymiou S, Turchetti V, Rahman F, Maqbool S, Salpietro V, Ibrahim SH, di Rosa G, Houlden H, Alharbi MN, Al-Sannaa NA, Bauer P, Zifarelli G, Estaras C, Hurst ACE, Thompson ML, Chassevent A, Smith-Hicks CL, de la Cruz X, Holtz AM, Elloumi HZ, Hajianpour MJ, Rieubland C, Braun D, Banka S, Genomic England Research Consortium, French DL, Heller EA, Saade M, Song H, Ming GL, Alkuraya FS, Agrawal PB, Reinberg D, Bhoj EJ, Martínez-Balbás MA, Akizu N
Nature communications 2023 Jul 11;14(1):4109
Nature communications 2023 Jul 11;14(1):4109
Discovery of precision targeting EZH2 degraders for triple-negative breast cancer.
Wang C, Chen X, Liu X, Lu D, Li S, Qu L, Yin F, Luo H, Zhang Y, Luo Z, Cui N, Kong L, Wang X
European journal of medicinal chemistry 2022 Aug 5;238:114462
European journal of medicinal chemistry 2022 Aug 5;238:114462
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Du Y, Zhong F, Cheng H, Li T, Chen Y, Tan P, Huang M, Liang T, Liu Y, Xia X, Fu W
Oxidative medicine and cellular longevity 2021;2021:4628050
Oxidative medicine and cellular longevity 2021;2021:4628050
Ezh1 regulates expression of Cpg15/Neuritin in mouse cortical neurons.
Utsunomiya S, Kishi Y, Tsuboi M, Kawaguchi D, Gotoh Y, Abe M, Sakimura K, Maeda K, Takemoto H
Drug discoveries & therapeutics 2021 May 11;15(2):55-65
Drug discoveries & therapeutics 2021 May 11;15(2):55-65
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EZH1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human EZH1. This antibody recognizes human, mouse, rat antigen. The EZH1 antibody has been validated for the following applications: ELISA, WB analysis.
