14068-1-AP

antibody from Proteintech Group

Targeting: ARID3A BRIGHT, DRIL1

Provider product page for 14068-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [14]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]
Immunohistochemistry [2]

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Product number: 14068-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#14068-1-AP, RRID:AB_2060390
Product name: ARID3A antibody
Antibody type: Polyclonal
Description: ARID3A antibody (Cat. #14068-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

ARID3A protein structure - 14068-1-AP shown in red.

Submitted references Functional remodeling of iNKT cells by sulfatide-reactive type II NKT cells reprograms alveolar macrophages to alleviate lung ischemia-reperfusion injury.

Li Q, Yin J, Lin Q, Xu Y, He J, Shi X, Huang S, Wang Y, Huang Y, Ding X, Yu H, Nie H
Communications biology 2026 Jan 17;9(1)

ARID3A Dysregulation Drives Colon Cancer Progression and Enhances Responsiveness to Aspirin.

Li J, Li M, Li Q, Wu Y, Shen Y, Li Y, Zhang M, Wang G, Zhu Y
Journal of cellular and molecular medicine 2026 Feb;30(3):e71038

ARID3A Promotes Tumor Progression by Activating TNF-α/NF-κB Signaling in Dual-Phenotype Hepatocellular Carcinoma.

Li M, Yang T, Huang J, Wu X, Chen J, Li J, Shi B, Zhang J, Xiang B
Journal of hepatocellular carcinoma 2025;12:2553-2564

ARID3A inhibits colorectal cancer cell stemness and drug-resistance by targeting a multitude of stemness-associated genes.

Gope TK, Pal D, Srivastava AK, Chatterjee B, Bose S, Ain R
Life sciences 2025 Jul 1;372:123642

LIN28B enhances the chemosensitivity of colon cancer cells via inducing genomic instability by upsetting the balance between the production and removal of reactive oxygen species.

Wang T, Weng M, Li K, Li G, Hu S, Hu Z, Li Y, Li M, Wu D, Liang Z, Yu F, Wang G, Li X
Cancer letters 2025 Apr 28;616:217572

Exosomal let-7b-5p deriving from parietal epithelial cells attenuate renal fibrosis through suppression of TGFβR1 and ARID3a in obstructive kidney disease.

Song A, Wang M, Xie K, Lu J, Zhao B, Wu W, Qian C, Hong W, Gu L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Oct 15;38(19):e70085

Personalized drug screening in patient-derived organoids of biliary tract cancer and its clinical application.

Ren X, Huang M, Weng W, Xie Y, Wu Y, Zhu S, Zhang Y, Li D, Lai J, Shen S, Lin J, Kuang M, Li X, Yu J, Xu L
Cell reports. Medicine 2023 Nov 21;4(11):101277

ARID3A plays a key regulatory role in palmitic acid-stimulated milk fat synthesis in mouse mammary epithelial cells.

Guo X, Qi H, Lin G, Yu J, Zhang M, Gao X
Cell biology international 2023 Jun;47(6):1106-1117

MiR-361-3p promotes tumorigenesis of osteosarcoma cells via targeting ARID3A.

Zhou D, Ji G, Wei G, Li Z, Yu N, Wang Y, Lin B, Zhang L, Yin Y
Tissue & cell 2022 Jun;76:101759

ARID3A promotes the chemosensitivity of colon cancer by inhibiting AKR1C3.

Li Y, Tang J, Li J, Du Y, Bai F, Yang L, Li X, Jin X, Wang T
Cell biology international 2022 Jun;46(6):965-975

ARID3A promotes the development of colorectal cancer by upregulating AURKA.

Tang J, Yang L, Li Y, Ning X, Chaulagain A, Wang T, Wang D
Carcinogenesis 2021 Apr 30;42(4):578-586

ARID3A Positivity Correlated With Favorable Prognosis in Patients With Residual Rectal Cancer After Neoadjuvant Chemoradiotherapy.

Yoon G, Park JY, Kim HJ, Choi GS, Kim JG, Kang BW, Kang MK, Seo AN
Anticancer research 2019 Jun;39(6):2845-2853

Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2.

Madison BB, Jeganathan AN, Mizuno R, Winslow MM, Castells A, Cuatrecasas M, Rustgi AK
PLoS genetics 2015 Aug;11(8):e1005408

High expression of AT-rich interactive domain 3A (ARID3A) is associated with good prognosis in colorectal carcinoma.

Song M, Kim H, Kim WK, Hong SP, Lee C, Kim H
Annals of surgical oncology 2014 Dec;21 Suppl 4:S481-9

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: K-562 cells were subjected to SDS PAGE followed by western blot with 14068-1-AP(ARID3A antibody) at dilution of 1:1500
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of HepG2 cells, using ARID3A antibody 14068-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human colon cancer using 14068-1-AP(ARID3A antibody) at dilution of 1:100 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human colon cancer using 14068-1-AP(ARID3A antibody) at dilution of 1:100 (under 40x lens)
Sample type: tissue