Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Blocking/Neutralizing [1]
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- Product number
- AF-215-NA - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal GM-CSF Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects human GM-CSF in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant mouse GM-CSF is observed. Neutralizes the biological activity of both recombinant human GM-CSF and natural human GM-CSF.
- Reactivity
- Human
- Host
- Goat
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Decidual GM-CSF is a critical common intermediate necessary for thrombin and TNF induced in-vitro fetal membrane weakening.
Low concentrations of recombinant granulocyte macrophage-colony stimulating factor derived from Chinese hamster ovary cells augments long-term bioactivity with delayed clearance in vitro.
Apoptotic neutrophils release macrophage migration inhibitory factor upon stimulation with tumor necrosis factor-alpha.
Secretory IgA induces antigen-independent eosinophil survival and cytokine production without inducing effector functions.
Toxoplasma gondii induces granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor secretion by human fibroblasts: implications for neutrophil apoptosis.
Toxoplasma gondii induces granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor secretion by human fibroblasts: implications for neutrophil apoptosis.
Bleomycin stimulates lung fibroblast and epithelial cell lines to release eosinophil chemotactic activity.
Kumar D, Moore RM, Nash A, Springel E, Mercer BM, Philipson E, Mansour JM, Moore JJ
Placenta 2014 Dec;35(12):1049-56
Placenta 2014 Dec;35(12):1049-56
Low concentrations of recombinant granulocyte macrophage-colony stimulating factor derived from Chinese hamster ovary cells augments long-term bioactivity with delayed clearance in vitro.
Hashimoto A, Tanaka T, Itoh Y, Yamagata A, Kitamura N, Tazawa R, Nakagaki K, Nakata K
Cytokine 2014 Aug;68(2):118-26
Cytokine 2014 Aug;68(2):118-26
Apoptotic neutrophils release macrophage migration inhibitory factor upon stimulation with tumor necrosis factor-alpha.
Daryadel A, Grifone RF, Simon HU, Yousefi S
The Journal of biological chemistry 2006 Sep 15;281(37):27653-61
The Journal of biological chemistry 2006 Sep 15;281(37):27653-61
Secretory IgA induces antigen-independent eosinophil survival and cytokine production without inducing effector functions.
Bartemes KR, Cooper KM, Drain KL, Kita H
The Journal of allergy and clinical immunology 2005 Oct;116(4):827-35
The Journal of allergy and clinical immunology 2005 Oct;116(4):827-35
Toxoplasma gondii induces granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor secretion by human fibroblasts: implications for neutrophil apoptosis.
Channon JY, Miselis KA, Minns LA, Dutta C, Kasper LH
Infection and immunity 2002 Nov;70(11):6048-57
Infection and immunity 2002 Nov;70(11):6048-57
Toxoplasma gondii induces granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor secretion by human fibroblasts: implications for neutrophil apoptosis.
Channon JY, Miselis KA, Minns LA, Dutta C, Kasper LH
Infection and immunity 2002 Nov;70(11):6048-57
Infection and immunity 2002 Nov;70(11):6048-57
Bleomycin stimulates lung fibroblast and epithelial cell lines to release eosinophil chemotactic activity.
Sato E, Koyama S, Robbins RA
The European respiratory journal 2000 Nov;16(5):951-8
The European respiratory journal 2000 Nov;16(5):951-8
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Cell Proliferation Induced by GM-CSF and Neutralization by Human GM-CSF Antibody. Cell Proliferation Induced by GM-CSF and Neutralization by Human GM-CSF Antibody.