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Western blot
Blocking/NeutralizingAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Blocking/Neutralizing [1]
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- Product number
- AF-415-NA - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal GM-CSF Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects mouse GM-CSF in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross-reactivity with recombinant rat GM-CSF is observed, approximately 10% cross-reactivity with recombinant human GM-CSF and recombinant feline GM-CSF is observed, and less than 2% cross-reactivity with recombinant porcine GM-CSF is observed.
- Reactivity
- Mouse
- Host
- Goat
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references GM-CSF-licensed CD11b+ lung dendritic cells orchestrate Th2 immunity to Blomia tropicalis.
A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex.
Recombinant Leishmania major secreting biologically active granulocyte-macrophage colony-stimulating factor survives poorly in macrophages in vitro and delays disease development in mice.
Recombinant Leishmania major secreting biologically active granulocyte-macrophage colony-stimulating factor survives poorly in macrophages in vitro and delays disease development in mice.
A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells.
Zhou Q, Ho AW, Schlitzer A, Tang Y, Wong KH, Wong FH, Chua YL, Angeli V, Mortellaro A, Ginhoux F, Kemeny DM
Journal of immunology (Baltimore, Md. : 1950) 2014 Jul 15;193(2):496-509
Journal of immunology (Baltimore, Md. : 1950) 2014 Jul 15;193(2):496-509
A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex.
Rafei M, Wu JH, Annabi B, Lejeune L, François M, Galipeau J
Blood 2007 Mar 1;109(5):2234-42
Blood 2007 Mar 1;109(5):2234-42
Recombinant Leishmania major secreting biologically active granulocyte-macrophage colony-stimulating factor survives poorly in macrophages in vitro and delays disease development in mice.
Dumas C, Muyombwe A, Roy G, Matte C, Ouellette M, Olivier M, Papadopoulou B
Infection and immunity 2003 Nov;71(11):6499-509
Infection and immunity 2003 Nov;71(11):6499-509
Recombinant Leishmania major secreting biologically active granulocyte-macrophage colony-stimulating factor survives poorly in macrophages in vitro and delays disease development in mice.
Dumas C, Muyombwe A, Roy G, Matte C, Ouellette M, Olivier M, Papadopoulou B
Infection and immunity 2003 Nov;71(11):6499-509
Infection and immunity 2003 Nov;71(11):6499-509
A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells.
Shih CC, Hu MC, Hu J, Weng Y, Yazaki PJ, Medeiros J, Forman SJ
Blood 2000 Mar 15;95(6):1957-66
Blood 2000 Mar 15;95(6):1957-66
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Cell Proliferation Induced by GM‑CSF and Neutralization by Mouse GM‑CSF Antibody. Cell Proliferation Induced by GM‑CSF and Neutralization by Mouse GM‑CSF Antibody.
