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- Antigen structure
- References [5]
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- Product number
- ABIN951765 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cyclin T1 (CCNT1) (AA 256-285), (Middle Region) antibody
- Antibody type
- Polyclonal
- Description
- Affinity chromatography on Protein A
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 256-285, Middle Region
- Vial size
- 0.4 mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Specificity of Hexim1 and Hexim2 complex formation with cyclin T1/T2, importin alpha and 7SK snRNA.
Cyclin T1 overexpression induces malignant transformation and tumor growth.
A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1.
Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells.
Recruitment of cdk9 to the immediate-early viral transcriptosomes during human cytomegalovirus infection requires efficient binding to cyclin T1, a threshold level of IE2 86, and active transcription.
Czudnochowski N, Vollmuth F, Baumann S, Vogel-Bachmayr K, Geyer M
Journal of molecular biology 2010 Jan 8;395(1):28-41
Journal of molecular biology 2010 Jan 8;395(1):28-41
Cyclin T1 overexpression induces malignant transformation and tumor growth.
Moiola C, De Luca P, Gardner K, Vazquez E, De Siervi A
Cell cycle (Georgetown, Tex.) 2010 Aug 1;9(15):3119-26
Cell cycle (Georgetown, Tex.) 2010 Aug 1;9(15):3119-26
A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1.
Schönichen A, Bigalke JM, Urbanke C, Grzesiek S, Dames SA, Geyer M
Biochemistry 2010 Apr 13;49(14):3083-91
Biochemistry 2010 Apr 13;49(14):3083-91
Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells.
Cho S, Schroeder S, Kaehlcke K, Kwon HS, Pedal A, Herker E, Schnoelzer M, Ott M
The EMBO journal 2009 May 20;28(10):1407-17
The EMBO journal 2009 May 20;28(10):1407-17
Recruitment of cdk9 to the immediate-early viral transcriptosomes during human cytomegalovirus infection requires efficient binding to cyclin T1, a threshold level of IE2 86, and active transcription.
Kapasi AJ, Clark CL, Tran K, Spector DH
Journal of virology 2009 Jun;83(11):5904-17
Journal of virology 2009 Jun;83(11):5904-17
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS
