Tissue expression
Cell line expression

GRM4

gene product
GPRC1D, mGlu4, MGLUR4 
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
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236 antibodies from 30 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
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antibodies-online
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3 antibodies
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1 antibody
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1 antibody
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3 antibodies
R&D Systems
1 antibody
Bioworld Technology, Inc
1 antibody
Boster Biological Technology
1 antibody
Acris Antibodies GmbH
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Abnova Corporation
2 antibodies
Creative Diagnostics
1 antibody
MyBioSource
5 antibodies
Abbexa
5 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
RayBiotech, Inc.
3 antibodies
GenWay
4 antibodies
United States Biological
14 antibodies
Leading Biology
3 antibodies
Abgent
3 antibodies
EMD Millipore
1 antibody