GRM4

gene product
GPRC1D, mGlu4, MGLUR4
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
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207 antibodies from 26 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Affinity Biosciences
2 antibodies
Biorbyt
14 antibodies
Invitrogen Antibodies
10 antibodies
antibodies-online
80 antibodies
LifeSpan BioSciences, Inc.
25 antibodies
GeneTex
4 antibodies
NovoPro Bioscience Inc.
3 antibodies
Aviva Systems Biology
1 antibody
OriGene
9 antibodies
Novus Biologicals
3 antibodies
R&D Systems
1 antibody
Bioworld Technology, Inc
1 antibody
St John's Laboratory
2 antibodies
Boster Biological Technology
1 antibody
Acris Antibodies GmbH
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Abnova Corporation
2 antibodies
Creative Diagnostics
1 antibody
MyBioSource
5 antibodies
RayBiotech, Inc.
3 antibodies
GenWay
4 antibodies
United States Biological
14 antibodies
Abgent
3 antibodies
Sigma-Aldrich
2 antibodies
EMD Millipore
1 antibody