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- References [14]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 15742-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15742-1-AP, RRID:AB_2209324
- Product name
- TRIM14 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TRIM14 antibody (Cat. #15742-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TRIM14 suppressed the progression of NSCLC via hexosamine biosynthesis pathway.
m(6)A-Mediated Upregulation of lncRNA CHASERR Promotes the Progression of Glioma by Modulating the miR-6893-3p/TRIM14 Axis.
Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells.
Exosomal circ_0091741 promotes gastric cancer cell autophagy and chemoresistance via the miR-330-3p/TRIM14/Dvl2/Wnt/β-catenin axis.
TRIM14 Overexpression Induces Chemoresistance and Malignant Behaviors of Hepatocellular Carcinoma Cells by Activating the STAT3/HIF-1α Pathway.
Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8(+) T cell exhaustion via TRIM14-IFN-β axis.
Hypoxia-Induced Upregulation of lncRNA ELFN1-AS1 Promotes Colon Cancer Growth and Metastasis Through Targeting TRIM14 via Sponging miR-191-5p.
Piperlongumine-inhibited TRIM14 signaling sensitizes glioblastoma cells to temozolomide treatment.
LncRNA GAS6-AS1 facilitates tumorigenesis and metastasis of colorectal cancer by regulating TRIM14 through miR-370-3p/miR-1296-5p and FUS.
Human mesenchymal stem cells derived exosomes inhibit the growth of acute myeloid leukemia cells via regulating miR-23b-5p/TRIM14 pathway.
Immunohistochemical validation study of 15-gene biomarker panel predictive of benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of JBR.10.
TRIM14 is a Putative Tumor Suppressor and Regulator of Innate Immune Response in Non-Small Cell Lung Cancer.
Expression profiling of TRIM protein family in THP1-derived macrophages following TLR stimulation.
TRIM14 regulates cell proliferation and invasion in osteosarcoma via promotion of the AKT signaling pathway.
Wei S, Ai M, Zhan Y, Yu J, Xie T, Hu Q, Fang Y, Huang X, Li Y
Carcinogenesis 2024 May 19;45(5):324-336
Carcinogenesis 2024 May 19;45(5):324-336
m(6)A-Mediated Upregulation of lncRNA CHASERR Promotes the Progression of Glioma by Modulating the miR-6893-3p/TRIM14 Axis.
Wu X, Fu M, Ge C, Zhou H, Huang H, Zhong M, Zhang M, Xu H, Zhu G, Hua W, Lv K, Yang H
Molecular neurobiology 2024 Aug;61(8):5418-5440
Molecular neurobiology 2024 Aug;61(8):5418-5440
Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells.
Liu Y, Yao X, Zhao Y, Fang D, Shi L, Yang L, Song G, Cai K, Li L, Deng Q, Li M, Luo Z
Cell reports 2023 Oct 31;42(10):113213
Cell reports 2023 Oct 31;42(10):113213
Exosomal circ_0091741 promotes gastric cancer cell autophagy and chemoresistance via the miR-330-3p/TRIM14/Dvl2/Wnt/β-catenin axis.
Chen Y, Liu H, Zou J, Cao G, Li Y, Xing C, Wu J
Human cell 2023 Jan;36(1):258-275
Human cell 2023 Jan;36(1):258-275
TRIM14 Overexpression Induces Chemoresistance and Malignant Behaviors of Hepatocellular Carcinoma Cells by Activating the STAT3/HIF-1α Pathway.
Xu W, Zhuang L, Zhu H, Mao A, Zhou J, Wang L
International journal of molecular sciences 2023 Aug 9;24(16)
International journal of molecular sciences 2023 Aug 9;24(16)
Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8(+) T cell exhaustion via TRIM14-IFN-β axis.
Ma X, Wang Q, Sun C, Agarwal I, Wu H, Chen J, Zhao C, Qi G, Teng Q, Yuan C, Yan S, Peng J, Li R, Song K, Zhang Q, Kong B
Cell reports 2023 Aug 29;42(8):112944
Cell reports 2023 Aug 29;42(8):112944
Hypoxia-Induced Upregulation of lncRNA ELFN1-AS1 Promotes Colon Cancer Growth and Metastasis Through Targeting TRIM14 via Sponging miR-191-5p.
Jing X, Du L, Shi S, Niu A, Wu J, Wang Y, Wang C
Frontiers in pharmacology 2022;13:806682
Frontiers in pharmacology 2022;13:806682
Piperlongumine-inhibited TRIM14 signaling sensitizes glioblastoma cells to temozolomide treatment.
Kuo YY, Ho KH, Shih CM, Chen PH, Liu AJ, Chen KC
Life sciences 2022 Nov 15;309:121023
Life sciences 2022 Nov 15;309:121023
LncRNA GAS6-AS1 facilitates tumorigenesis and metastasis of colorectal cancer by regulating TRIM14 through miR-370-3p/miR-1296-5p and FUS.
Chen Q, Zhou L, Ma D, Hou J, Lin Y, Wu J, Tao M
Journal of translational medicine 2022 Aug 12;20(1):356
Journal of translational medicine 2022 Aug 12;20(1):356
Human mesenchymal stem cells derived exosomes inhibit the growth of acute myeloid leukemia cells via regulating miR-23b-5p/TRIM14 pathway.
Cheng H, Ding J, Tang G, Huang A, Gao L, Yang J, Chen L
Molecular medicine (Cambridge, Mass.) 2021 Oct 16;27(1):128
Molecular medicine (Cambridge, Mass.) 2021 Oct 16;27(1):128
Immunohistochemical validation study of 15-gene biomarker panel predictive of benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of JBR.10.
Grieve S, Ding K, Moore J, Finniss M, Ray A, Lees M, Hossain F, Murugesan A, Agar J, Acar C, Taylor J, Shepherd FA, Reiman T
ESMO open 2020 Mar;5(2)
ESMO open 2020 Mar;5(2)
TRIM14 is a Putative Tumor Suppressor and Regulator of Innate Immune Response in Non-Small Cell Lung Cancer.
Hai J, Zhu CQ, Wang T, Organ SL, Shepherd FA, Tsao MS
Scientific reports 2017 Jan 6;7:39692
Scientific reports 2017 Jan 6;7:39692
Expression profiling of TRIM protein family in THP1-derived macrophages following TLR stimulation.
Jiang MX, Hong X, Liao BB, Shi SZ, Lai XF, Zheng HY, Xie L, Wang Y, Wang XL, Xin HB, Fu M, Deng KY
Scientific reports 2017 Feb 17;7:42781
Scientific reports 2017 Feb 17;7:42781
TRIM14 regulates cell proliferation and invasion in osteosarcoma via promotion of the AKT signaling pathway.
Xu G, Guo Y, Xu D, Wang Y, Shen Y, Wang F, Lv Y, Song F, Jiang D, Zhang Y, Lou Y, Meng Y, Yang Y, Kang Y
Scientific reports 2017 Feb 16;7:42411
Scientific reports 2017 Feb 16;7:42411
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- L02 cells were subjected to SDS PAGE followed by western blot with 15742-1-AP(TRIM14 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using TRIM14 antibody 15742-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 15742-1-AP(TRIM14 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 15742-1-AP(TRIM14 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
